[HTML][HTML] Candida albicans biofilms: development, regulation, and molecular mechanisms

M Gulati, CJ Nobile - Microbes and infection, 2016 - Elsevier
A major virulence attribute of Candida albicans is its ability to form biofilms, densely packed
communities of cells adhered to a surface. These biofilms are intrinsically resistant to …

Candida albicans Biofilms and Human Disease

CJ Nobile, AD Johnson - Annual review of microbiology, 2015 - annualreviews.org
In humans, microbial cells (including bacteria, archaea, and fungi) greatly outnumber host
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this …

Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

AN Schep, JD Buenrostro, SK Denny… - Genome …, 2015 - genome.cshlp.org
Transcription factors canonically bind nucleosome-free DNA, making the positioning of
nucleosomes within regulatory regions crucial to the regulation of gene expression. Using …

Controlling gene expression in response to stress

E De Nadal, G Ammerer, F Posas - Nature Reviews Genetics, 2011 - nature.com
Acute stress puts cells at risk, and rapid adaptation is crucial for maximizing cell survival.
Cellular adaptation mechanisms include modification of certain aspects of cell physiology …

A recently evolved transcriptional network controls biofilm development in Candida albicans

CJ Nobile, EP Fox, JE Nett, TR Sorrells, QM Mitrovich… - Cell, 2012 - cell.com
A biofilm is an organized, resilient group of microbes in which individual cells acquire
properties, such as drug resistance, that are distinct from those observed in suspension …

Pathogenesis and Clinical Relevance of Candida Biofilms in Vulvovaginal Candidiasis

C Rodríguez-Cerdeira, E Martínez-Herrera… - Frontiers in …, 2020 - frontiersin.org
The ability of Candida spp. to form biofilms is crucial for its pathogenicity, and thus, it should
be considered an important virulence factor in vulvovaginal candidiasis (VVC) and recurrent …

Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis

KN Chang, S Zhong, MT Weirauch, G Hon, M Pelizzola… - elife, 2013 - elifesciences.org
The gaseous plant hormone ethylene regulates a multitude of growth and developmental
processes. How the numerous growth control pathways are coordinated by the ethylene …

Response to hyperosmotic stress

H Saito, F Posas - Genetics, 2012 - academic.oup.com
An appropriate response and adaptation to hyperosmolarity, ie., an external osmolarity that
is higher than the physiological range, can be a matter of life or death for all cells. It is …

Transcriptional Regulation in Saccharomyces cerevisiae: Transcription Factor Regulation and Function, Mechanisms of Initiation, and Roles of Activators and …

S Hahn, ET Young - Genetics, 2011 - academic.oup.com
Here we review recent advances in understanding the regulation of mRNA synthesis in
Saccharomyces cerevisiae. Many fundamental gene regulatory mechanisms have been …

Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration in mice

Y Cheng, Y Yin, A Zhang, AM Bernstein… - Nature …, 2022 - nature.com
The inability of neurons to regenerate long axons within the CNS is a major impediment to
improving outcome after spinal cord injury, stroke, and other CNS insults. Recent advances …