Biofilm refers to the complex, sessile communities of microbes found either attached to a
surface or buried firmly in an extracellular matrix as aggregates. The biofilm matrix …

Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various
important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di …

Recent studies of bacterial cellulose biosynthesis, including structural characterization of a
functional cellulose synthase complex, provided the first mechanistic insight into this …

Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …

Bacterial cellulose (BC) nanofibers are one of the stiffest organic materials produced by
nature. It consists of pure cellulose without the impurities that are commonly found in plant …

On the stage of bacterial signal transduction and regulation, bis-(3′-5′)-cyclic dimeric
guanosine monophosphate (c-di-GMP) has long played the part of Sleeping Beauty. c-di …

Biofilms are communities of microorganisms that live attached to surfaces. Biofilm formation
has received much attention in the last decade, as it has become clear that virtually all types …

Morphological form in multicellular aggregates emerges from the interplay of genetic
constitution and environmental signals. Bacterial macrocolony biofilms, which form intricate …

The ability of Salmonella to form complex surface-associated communities, called biofilms,
contributes to its resistance and persistence in both host and non-host environments and is …

Experimental approaches primarily focused on genetic and microscopic techniques have
laid the foundation for our current models of bacterial biofilm formation. This work has …