[HTML][HTML] Role of HLA-B27 in the pathogenesis of ankylosing spondylitis

B Chen, J Li, C He, D Li, W Tong… - Molecular medicine …, 2017 - spandidos-publications.com
The study of ankylosing spondylitis (AS) has made significant progress over the last decade.
Genome-wide association studies have identified and further substantiated the role of …

HLA-B27

P Bowness - Annual review of immunology, 2015 - annualreviews.org
Possession of the human leukocyte antigen (HLA) class I molecule B27 is strongly
associated with ankylosing spondylitis (AS), but the pathogenic role of HLA-B27 is unknown …

The pathogenetic role of HLA-B27 and its subtypes

MA Khan, A Mathieu, R Sorrentino, N Akkoc - Autoimmunity reviews, 2007 - Elsevier
The strong association between HLA-B27 and ankylosing spondylitis has been known for
more than 33 years, but the enigma of the pathogenetic role of the gene and its product has …

Pathogenesis of ankylosing spondylitis and reactive arthritis

TH Kim, WS Uhm, RD Inman - Current opinion in rheumatology, 2005 - journals.lww.com
Pathogenesis of ankylosing spondylitis and reactive arthriti... : Current Opinion in Rheumatology
Pathogenesis of ankylosing spondylitis and reactive arthritis : Current Opinion in Rheumatology …

What is the role of HLA-B27 in spondyloarthropathies?

A Chatzikyriakidou, PV Voulgari, AA Drosos - Autoimmunity reviews, 2011 - Elsevier
HLA-B27 (Human Leukocyte Antigen-B27) accounts approximately for the one third of the
overall genetic susceptibility to spondylorthropathies (SpAs). Up to 70 HLA-B27 subtypes …

When is arthritis reactive?

SS Hamdulay, SJ Glynne, A Keat - Postgraduate medical journal, 2006 - academic.oup.com
Reactive arthritis is an important cause of lower limb oligoarthritis, mainly in young adults. It
is one of the spondyloarthropathy family; it is distinguishable from other forms of …

Ankylosing spondylitis: a contemporary perspective on diagnosis and treatment

M Mansour, GS Cheema, SM Naguwa… - Seminars in arthritis and …, 2007 - Elsevier
OBJECTIVES: In recent years, great progress has been made in the development of
diagnostic tools, therapeutic approaches, and validated outcome measures in the …

The pathogenesis of ankylosing spondylitis

MF Shamji, M Bafaquh, E Tsai - Neurosurgical focus, 2008 - thejns.org
✓ Ankylosing spondylitis (AS) is a chronic inflammatory disease that can cause significant
functional complications by affecting the sacroiliac joints and axial skeleton. Despite a …

HLA–B27 subtypes predisposing to ankylosing spondylitis accumulate in an endoplasmic reticulum–derived compartment apart from the peptide‐loading complex

N Jah, A Jobart‐Malfait, K Ermoza… - Arthritis & …, 2020 - Wiley Online Library
Objective It was previously shown that HLA–B27 subtypes predisposing to spondyloarthritis
(SpA), ie, B* 27: 02, B* 27: 05, and B* 27: 07, displayed an increased propensity to form …

Evolving patterns of reactive arthritis

KM Hayes, RJP Hayes, MA Turk, JE Pope - Clinical rheumatology, 2019 - Springer
Objective To characterize rheumatologists' perspectives on evolving trends of reactive
arthritis (ReA). Methods After ethics approval, 548 members of the Canadian Rheumatology …