Growth hormone (GH) research and its clinical application for the treatment of growth disorders span more than a century. During the first half of the 20th century, clinical …
PF Collett-Solberg, G Ambler, PF Backeljauw… - Hormone research in …, 2019 - karger.com
Abstract The Growth Hormone Research Society (GRS) convened a Workshop in March 2019 to evaluate the diagnosis and therapy of short stature in children. Forty-six …
CL Deal, M Tony, C Höybye, DB Allen… - The Journal of …, 2013 - academic.oup.com
Context: Recombinant human GH (rhGH) therapy in Prader-Willi syndrome (PWS) has been used by the medical community and advocated by parental support groups since its …
MH Aguiar-Oliveira, A Bartke - Endocrine reviews, 2019 - academic.oup.com
The important role of GH in the control of mammalian longevity was first deduced from extended longevity of mice with genetic GH deficiency (GHD) or GH resistance. Mice with …
Growth hormone deficiency (GHD) is a clinical syndrome that can manifest either as isolated or associated with additional pituitary hormone deficiencies. Although diminished height …
AD Rogol, GF Hayden - The Journal of pediatrics, 2014 - Elsevier
Accurate measurement of height and weight using standardized techniques is a fundamental component of pediatric medical visits. Calculation of height velocity over time …
PG Murray, MT Dattani, PE Clayton - Archives of disease in childhood, 2016 - adc.bmj.com
Growth hormone deficiency (GHD) is a rare but important cause of short stature in childhood with a prevalence of 1 in 4000. The diagnosis is currently based on an assessment of …
MB Ranke - Frontiers in endocrinology, 2021 - frontiersin.org
The syndrome of impaired GH secretion (GH deficiency) in childhood and adolescence had been identified at the end of the 19th century. Its non-acquired variant (naGHD) is, at …
Short stature remains the most common reason for referral to a pediatric Endocrinologist and its management remains a challenge. One of the main controversies is the diagnosis of …