In the post-genomic era, the goal of personalized medicine is to determine the correlation
between genotype and phenotype. Developing high-throughput genotyping technologies …

Congenital anomalies of the kidney and urinary tract (CAKUT) comprise a large variety of
malformations that arise from defective kidney or urinary tract development and frequently …

The female reproductive tract receives the oocytes for fertilization, supports the development
of the fetus and provides the passage for birth. Although abnormalities of this organ system …

Congenital anomalies of the kidney and urinary tract (CAKUT) cover a wide range of
structural malformations that result from defects in the morphogenesis of the kidney and/or …

Extraembryonic endoderm (ExE) is differentiated from the inner cell mass of the late
blastocyst-stage embryo to form visceral and parietal endoderm, both of which have an …

Congenital anomalies of the kidney and urinary tract (CAKUT) are the most frequent form of
malformation at birth and represent the cause of 40–50% of pediatric and 7% of adult end …

Background: Hepatocyte nuclear factor-1 beta (HNF-1β) is a widely distributed transcription
factor which plays a critical role in embryonic development of the kidney, pancreas, liver …

The Müllerian duct (MD) forms the female reproductive tract (FRT) consisting of the oviducts,
uterus, cervix, and upper vagina. FRT function is vital to fertility, providing the site of …

To date, more than 30 genes have been linked to monogenic diabetes. Candidate gene and
genome-wide association studies have identified> 50 susceptibility loci for common type 1 …

The major forms of diabetes are characterized by pancreatic islet β-cell dysfunction and
decreased β-cell numbers, raising hope for cell replacement therapy. Although human islet …