Intestinal inflammatory diseases, such as Crohn's disease, ulcerative colitis, and necrotizing
enterocolitis, are becoming increasingly prevalent. While knowledge of the pathogenesis of …

Abstract Sepsis in the United States has an estimated annual healthcare cost of $16.7 billion
and leads to 120 000 deaths. Insufficient development in both medical diagnosis and …

Defective intestinal epithelial tight junction (TJ) barrier has been shown to be a pathogenic
factor in the development of intestinal inflammation. Interleukin-6 (IL-6) is a pleiotropic, pro …

Adult hematopoietic stem and progenitor cells (HSPCs) respond directly to inflammation and
infection, causing both acute and persistent changes to quiescence, mobilization, and …

OBJECTIVE. The goal was to determine the utility of neutrophil CD64 as a diagnostic marker
for sepsis in neonates. METHODS. A prospective study that enrolled consecutive infants with …

Background Sepsis is a major health issue in preterm infants. Biomarkers are used to
diagnose and monitor patients with sepsis, but C-reactive protein (CRP) is proven not …

Preterm birth is associated with immature digestive function that may require the use of total
parenteral nutrition and special oral feeding regimens. Little is known about the responses …

Monocytes from many critically ill patients show a low level of major histocompatibility
complex type II (MHC II) expression. This phenomenon is believed to play a role in these …

Neonatal necrotizing enterocolitis: an overview : Current Opinion in Infectious Diseases
Neonatal necrotizing enterocolitis: an overview : Current Opinion in Infectious Diseases Log in …

The inflammatory response plays a major role in the induction of several neonatal diseases.
We hypothesize that an imbalance between the pro-and anti-inflammatory response is …