Vaccination represents the best line of defense against infectious diseases and is crucial in
curtailing pandemic spread of emerging pathogens to which a population has limited …

Nanoparticle-based drug delivery system (DDS) is considered promising for cancer
treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved …

Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …

Biological barriers to drug transport prevent successful accumulation of nanotherapeutics
specifically at diseased sites, limiting efficacious responses in disease processes ranging …

Immunogenic cell death (ICD, also known as immunogenic apoptosis) of malignant cells is
confirmed to activate the host immune system to prevent, control, and eliminate tumors …

Nanoparticle (NP) drug delivery systems (5− 250 nm) have the potential to improve current
disease therapies because of their ability to overcome multiple biological barriers and …

Cancer immunotherapy is an innovative treatment strategy to enhance the ability of the
immune system to recognize and eliminate cancer cells. However, dose limitations, low …

Electron microscopy played a key role in establishing cell biology as a discipline, by
producing fundamental insights into cellular organization and ultrastructure. Many seminal …

The complex functions of the liver in biosynthesis, metabolism, clearance, and host defense
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …

Microbial infections present a major global healthcare challenge, in large part because of
the development of microbial resistance to the currently approved antimicrobial drugs. This …