The accumulation and deposition of α-synuclein aggregates in brain tissue is the main event
in the pathogenesis of different neurodegenerative disorders grouped under the term of …

Since chronic wasting disease (CWD) was first identified nearly 50 years ago in a captive
mule deer herd in the Rocky Mountains of the United States, it has slowly spread across …

Prions propagate as multiple strains in a wide variety of mammalian species. The detection
of all such strains by a single ultrasensitive assay such as Real Time Quaking-induced …

Recent work with prion diseases and synucleinopathies indicates that accurate diagnostic
methods for protein-folding diseases can be based on the ultrasensitive, amplified …

Efforts to contain the spread of chronic wasting disease (CWD), a fatal, contagious prion
disease of cervids, would be aided by the availability of additional diagnostic tools. RT-QuIC …

Hypochlorous acid (HOCl) is produced naturally by neutrophils and other cells to kill
conventional microbes in vivo. Synthetic preparations containing HOCl can also be effective …

Cervids are affected by a neurologic disease that is always fatal to individuals and has
population effects. This disease is called chronic wasting disease (CWD) and is caused by a …

Chronic wasting disease (CWD) is a transmissible prion disorder, primarily affecting free-
ranging and captive cervids in North America (United States and Canada), South Korea, and …

Chronic wasting disease (CWD) is a relatively new and burgeoning prion epidemic of deer,
elk, reindeer, and moose, which are members of the cervid family. While the disease was …

Chronic wasting disease (CWD), a transmissible spongiform encephalopathy of cervids, was
first documented nearly 50 years ago in Colorado and Wyoming and has since spread to …