Paramyxovirus fusion and entry: multiple paths to a common end

A Chang, RE Dutch - Viruses, 2012 - mdpi.com
The paramyxovirus family contains many common human pathogenic viruses, including
measles, mumps, the parainfluenza viruses, respiratory syncytial virus, human …

Activation of paramyxovirus membrane fusion and virus entry

TS Jardetzky, RA Lamb - Current opinion in virology, 2014 - Elsevier
Highlights•Most paramyxoviruses require attachment and fusion (F) proteins for cell
entry.•Competing 'clamp'and 'provocateur'models have been proposed as entry …

[HTML][HTML] Paramyxovirus glycoprotein incorporation, assembly and budding: a three way dance for infectious particle production

F El Najjar, AP Schmitt, RE Dutch - Viruses, 2014 - mdpi.com
Paramyxoviruses are a family of negative sense RNA viruses whose members cause
serious diseases in humans, such as measles virus, mumps virus and respiratory syncytial …

Subnanometer structure of an enveloped virus fusion complex on viral surface reveals new entry mechanisms

TC Marcink, G Zipursky, W Cheng, K Stearns… - Science …, 2023 - science.org
Paramyxoviruses—including important pathogens like parainfluenza, measles, and Nipah
viruses—use a receptor binding protein [hemagglutinin-neuraminidase (HN) for …

Structure and organization of paramyxovirus particles

RM Cox, RK Plemper - Current opinion in virology, 2017 - Elsevier
Highlights•Cryo-electron tomography reconstructions of paramyxovirus particles have
yielded novel insight into virion assembly and organization.•Newcastle disease virus matrix …

Receptor-mediated cell entry of paramyxoviruses: Mechanisms, and consequences for tropism and pathogenesis

CK Navaratnarajah, AR Generous, I Yousaf… - Journal of Biological …, 2020 - ASBMB
Research in the last decade has uncovered many new paramyxoviruses, airborne agents
that cause epidemic diseases in animals including humans. Most paramyxoviruses enter …

Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies

NV Johnson, RC van Scherpenzeel… - Nature …, 2024 - nature.com
Respirovirus 3 is a leading cause of severe acute respiratory infections in vulnerable human
populations. Entry into host cells is facilitated by the attachment glycoprotein and the fusion …

Potent henipavirus neutralization by antibodies recognizing diverse sites on Hendra and Nipah virus receptor binding protein

J Dong, RW Cross, MP Doyle, N Kose, JJ Mousa… - Cell, 2020 - cell.com
Summary Hendra (HeV) and Nipah (NiV) viruses are emerging zoonotic pathogens in the
Henipavirus genus causing outbreaks of disease with very high case fatality rates. Here, we …

[HTML][HTML] Timing is everything: Fine-tuned molecular machines orchestrate paramyxovirus entry

S Bose, TS Jardetzky, RA Lamb - Virology, 2015 - Elsevier
The Paramyxoviridae include some of the great and ubiquitous disease-causing viruses of
humans and animals. In most paramyxoviruses, two viral membrane glycoproteins, fusion …

Unraveling a three-step spatiotemporal mechanism of triggering of receptor-induced Nipah virus fusion and cell entry

Q Liu, JA Stone, B Bradel-Tretheway, J Dabundo… - PLoS …, 2013 - journals.plos.org
Membrane fusion is essential for entry of the biomedically-important paramyxoviruses into
their host cells (viral-cell fusion), and for syncytia formation (cell-cell fusion), often induced …