Abstract The Framingham Heart Study (FHS) has conducted seminal research defining
cardiovascular disease (CVD) risk factors and fundamentally shaping public health …

Atherosclerosis is the main underlying pathology for many cardiovascular diseases (CVDs),
which are the leading cause of death globally and represent a serious health crisis …

We consider our current understanding and therapy of cardiovascular diseases (CVD) state-
of-the-art, but heart disease is still a problem because there is still a lot that we do not know …

Background A person's rate of aging has important implications for his/her risk of death and
disease; thus, quantifying aging using observable characteristics has important applications …

Dietary guidelines continue to recommend restricting intake of saturated fats. This
recommendation follows largely from the observation that saturated fats can raise levels of …

Endothelial dysfunction is an early event in experimental studies of atherogenesis,
preceding formation of plaques. We have devised a non-invasive method for testing …

A unique, in-depth discussion of the uses and conduct of cost-effectiveness analyses (CEAs)
as decision-making aids in the health and medical fields, this volume is the product of over …

The inability of current recommendations to control the epidemic of diabetes, the specific
failure of the prevailing low-fat diets to improve obesity, cardiovascular risk, or general …

The leadership of the National Lipid Association convened an Expert Panel to develop a
consensus set of recommendations for patient-centered management of dyslipidemia in …

Dyslipidemia is an important risk factor for coronary artery disease and stroke. Long-term,
prospective epidemiologic studies have consistently shown that persons with healthier …