Analysis of anti-rheumatic activity of Nyctanthes arbor-tristis via in vivo and pharmacovigilance approaches

A Sharma, A Goel, Z Lin - Frontiers in Pharmacology, 2023 - frontiersin.org
Introduction: Rheumatoid arthritis (RA) is an immune-mediated disease associated with
chronic inflammation of numerous joints. Nyctanthes arbor-tristis (NAT) is a traditional …

Synthesis and biological evaluation of chrysin derivatives containing α-lipoic acid for the treatment of inflammatory bowel disease

P Zhao, Y Hou, T Yan, J Kang, Y Tian, J Li… - Frontiers in …, 2024 - frontiersin.org
This study introduces newly discovered chrysin derivatives that show potential as candidate
molecules for treating inflammatory bowel disease (IBD). Compound 4b, among the …

Anti-arthritic effect of spirocyclopiperazinium bromide DXL-A-24 in CFA-induced arthritic rats and its mechanism

T Wang, H Yang, X Wang, R Li, Y Jiang, J Ye - European Journal of …, 2024 - Elsevier
This study aimed to investigate the effect of spirocyclopiperazinium bromide DXL-A-24 on
complete Freund's adjuvant (CFA)-induced arthritis and its underlying mechanism in rats. A …

The Possible Ameliorative Role of Chrysin and Zinc on Lead Acetate Induced Nephrotoxicity in Adult Albino Rats (Biochemical, Histological and Immunohistochemical …

HI El-Kerdasy, AG Metwally - Egyptian Journal of Hospital Medicine, 2024 - journals.ekb.eg
Background and Objective: Chrysin has been used for suppression of inducible nitric oxide
synthase. Zinc inhibits the production of oxygen-free radicals. This study aimed to assess the …