Carbapenem resistance: a review

FS Codjoe, ES Donkor - Medical Sciences, 2017 - mdpi.com
Carbapenem resistance is a major and an on-going public health problem globally. It occurs
mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas …

Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods

CR Lee, JH Lee, KS Park, YB Kim, BC Jeong… - Frontiers in …, 2016 - frontiersin.org
The emergence of carbapenem-resistant Gram-negative pathogens poses a serious threat
to public health worldwide. In particular, the increasing prevalence of carbapenem-resistant …

Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river

S Rodriguez-Mozaz, S Chamorro, E Marti, B Huerta… - Water research, 2015 - Elsevier
Antibiotic resistance has become a major health concern; thus, there is a growing interest in
exploring the occurrence of antibiotic resistance genes (ARGs) in the environment as well as …

Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases

LS Munoz-Price, L Poirel, RA Bonomo… - The Lancet infectious …, 2013 - thelancet.com
Klebsiella pneumoniae carbapenemases (KPCs) were originally identified in the USA in
1996. Since then, these versatile β-lactamases have spread internationally among Gram …

Controlling hospital-acquired infection: focus on the role of the environment and new technologies for decontamination

SJ Dancer - Clinical microbiology reviews, 2014 - Am Soc Microbiol
There is increasing interest in the role of cleaning for managing hospital-acquired infections
(HAI). Pathogens such as vancomycin-resistant enterococci (VRE), methicillin-resistant …

The impact of on-site hospital wastewater treatment on the downstream communal wastewater system in terms of antibiotics and antibiotic resistance genes

GK Paulus, LM Hornstra, N Alygizakis… - International journal of …, 2019 - Elsevier
This study quantified antibiotic and antibiotic resistance gene (ARG) concentrations in
hospital and communal wastewaters as well as the influents and effluents of the receiving …

A Review of Carbapenem Resistance in Enterobacterales and Its Detection Techniques

O Caliskan-Aydogan, EC Alocilja - Microorganisms, 2023 - mdpi.com
Infectious disease outbreaks have caused thousands of deaths and hospitalizations, along
with severe negative global economic impacts. Among these, infections caused by …

Origin and evolution of antibiotic resistance: the common mechanisms of emergence and spread in water bodies

A Lupo, S Coyne, TU Berendonk - Frontiers in microbiology, 2012 - frontiersin.org
The environment, and especially freshwater, constitutes a reactor where the evolution and
the rise of new resistances occur. In water bodies such as waste water effluents, lakes, and …

Genomic analysis of hospital plumbing reveals diverse reservoir of bacterial plasmids conferring carbapenem resistance

RA Weingarten, RC Johnson, S Conlan, AM Ramsburg… - MBio, 2018 - Am Soc Microbiol
The hospital environment is a potential reservoir of bacteria with plasmids conferring
carbapenem resistance. Our Hospital Epidemiology Service routinely performs extensive …

The threat of carbapenem-resistant bacteria in the environment: Evidence of widespread contamination of reservoirs at a global scale

MC Mills, J Lee - Environmental Pollution, 2019 - Elsevier
Environmental reservoirs of antibiotic resistance (AR) are a growing concern that are
gathering more attention as potential sources for human infection. Carbapenem-resistant …