Association between lead exposure and DNA damage (genotoxicity): systematic review and meta-analysis

R Nagaraju, R Kalahasthi, R Balachandar… - Archives of …, 2022 - Springer
Studies suggest that chronic lead (Pb) exposure may induce deoxyribonucleic acid (DNA)
damage. However, there is no synthesised evidence in this regard. We systematically …

Cadmium exposure and DNA damage (genotoxicity): a systematic review and meta-analysis

R Nagaraju, R Kalahasthi, R Balachandar… - Critical Reviews in …, 2022 - Taylor & Francis
Existing literature suggests an association between chronic cadmium (Cd) exposure and the
induction of DNA damage and genotoxicity. However, observations from individual studies …

Exposure to particulate PAHs on potential genotoxicity and cancer risk among school children living near the petrochemical industry

NA Sopian, J Jalaludin, S Abu Bakar… - International Journal of …, 2021 - mdpi.com
This study aimed to assess the association of exposure to particle-bound (PM2. 5) polycyclic
aromatic hydrocarbons (PAHs) with potential genotoxicity and cancer risk among children …

Toxic effect of polycyclic aromatic hydrocarbons (PAHs) on co-culture model of human alveolar epithelial cells (A549) and macrophages (THP-1)

P Takam, A Schäffer, S Laovitthayanggoon… - Environmental Sciences …, 2024 - Springer
Polycyclic aromatic hydrocarbons (PAHs) are particulate matter bound environmental
contaminants known to cause adverse effects on human health. The toxicity of carcinogenic …

The Comet Assay as a Tool in Human Biomonitoring Studies of Environmental and Occupational Exposure to Chemicals—A Systematic Scoping Review

C Ladeira, P Møller, L Giovannelli, G Gajski, A Haveric… - Toxics, 2024 - mdpi.com
Biomonitoring of human populations exposed to chemical substances that can act as
potential mutagens or carcinogens, may enable the detection of damage and early disease …

Expression deregulation of genes related to DNA repair and lead toxicity in occupationally exposed industrial workers

Z Akram, I Mahjabeen, M Batool, S Kanwal… - International archives of …, 2023 - Springer
Objective Globally millions of people working in various industries and are exposed to
different toxins which may affect their genetic stability and DNA integrity. Present study was …

[HTML][HTML] Use of micronucleus cytome assays with buccal cells for the detection of genotoxic effects: a systematic review and meta-analysis of occupational exposures …

G Wultsch, A Nersesyan, M Kundi, M Fenech… - … Research-Reviews in …, 2024 - Elsevier
Micronucleus (MN) assays with buccal cells are at present widely used to investigate
occupational exposures to genotoxic carcinogens. This article describes their use for the …

Circulating lead modifies hexavalent chromium-induced genetic damage in a chromate-exposed population: An epidemiological study

G Hu, C Long, L Hu, BP Xu, T Chen, X Gao… - Science of the total …, 2021 - Elsevier
Chromium (Cr) can coexist with other heavy metals in the blood of chronically chromate-
exposed individuals. However, few studies have explored the health impacts of other …

Evaluation of oxidative stress parameters and genotoxic effects in patients with work-related asthma and silicosis

OK Kurt, D Ergun, HG Anlar, M Hazar… - … of Occupational and …, 2023 - journals.lww.com
Objective To determine the mechanistic roles of oxidative stress, inflammation, and
genotoxicity parameters in patients with work-related asthma (WRA) and silicosis. Methods …

K2Cr2O7-induced DNA damage in HT1080 cells: Electrochemical signal response mechanism

C Ye, H Guo, Y Wei, S Zhou, S Zhang, J Li, J Cui… - International Journal of …, 2024 - Elsevier
The existing DNA damage detection technology cannot meet the current detection
requirements. It is critical to build new methods and discover novel biomarkers. In this study …