Ginsenoside Rg1 in neurological diseases: From bench to bedside

S Yang, J Wang, P Cheng, L Chen, J Hu… - Acta Pharmacologica …, 2023 - nature.com
Ginseng has been used in China as a superior medicinal material for thousands of years
that can nourish the five internal organs, calm the mind and benefit wisdom. Due to its anti …

Panax ginseng against myocardial ischemia/reperfusion injury: A review of preclinical evidence and potential mechanisms

J Chen, Q Huang, J Li, Y Yao, W Sun, Z Zhang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Panax ginseng CA Meyer (P. ginseng) is effective in the
prevention and treatment of myocardial ischemia-reperfusion (I/R) injury. The mechanism by …

[HTML][HTML] Pharmacological properties of ginsenoside Re

XY Gao, GC Liu, JX Zhang, LH Wang, C Xu… - Frontiers in …, 2022 - frontiersin.org
Ginsenoside Re is a protopanaxatriol-type saponin extracted from the berry, leaf, stem,
flower bud, and root of Panax ginseng. In recent years, ginsenoside Re (Re) has been …

A comprehensive system review of pharmacological effects and relative mechanisms of Ginsenoside Re: Recent advances and future perspectives

J Cai, K Huang, S Han, R Chen, Z Li, Y Chen, B Chen… - Phytomedicine, 2022 - Elsevier
ABSTRACT Background: Ginsenoside Re (Re) belongs to protopanaxatriol saponins and
exists in Panax ginseng, Panax quinquefolium, Panax notoginseng, and other plants in the …

[HTML][HTML] Mitochondrial dysfunction in heart diseases: Potential therapeutic effects of Panax ginseng

X Cao, F Yao, B Zhang, X Sun - Frontiers in Pharmacology, 2023 - frontiersin.org
Heart diseases have a high incidence and mortality rate, and seriously affect people's
quality of life. Mitochondria provide energy for the heart to function properly. The process of …

Advances in the role of natural products in human gene expression

C Gang, Z Di, W Cheng-Min, LI Ning - Chinese Journal of Natural Medicines, 2022 - Elsevier
Natural products (NPs), especially those from traditional herbal medicines, can evidently
modulate human gene expression at multiple levels, leading to a wide diversity of …

Epigallocatechin-3-gallate protects cardiomyocytes from hypoxia-reoxygenation damage via raising autophagy related 4C expression

P Liu, J Huang, W Mei, X Zeng, C Wang, C Wen… - …, 2021 - Taylor & Francis
Myocardial ischemia/reperfusion (I/R) injury is a serious issue during the therapy of
myocardial infarction. Herein, we explored the beneficial influence of Epigallocatechin-3 …

Explaining and predicting allostery with allosteric database and modern analytical techniques

J Zha, M Li, R Kong, S Lu, J Zhang - Journal of Molecular Biology, 2022 - Elsevier
Allostery is a phenomenon that the protein activity is regulated when a non-functional site on
it is bounded. This phenomenon is important in life process and disease therapy. However, it …

Cyanidin-3-O-glucoside from blueberry anthocyanin extracts protects ARPE-19 cells against high glucose damage via REDD1/GSK3β pathway

R Li, Z Ye, Y Xu, Y Liu - Food Bioscience, 2023 - Elsevier
The retinal pigment epithelium (RPE) serves dual roles: it acts as a selective barrier and also
as a regulator for the photoreceptor layer situated above it. The RPE is considered a crucial …

Integration of network pharmacology and proteomics analysis to identify key target pathways of Ginsenoside Re for myocardial ischemia

J Cai, Y Zhan, K Huang, S Han, Z Lin, R Chen, Q Luo… - Phytomedicine, 2024 - Elsevier
Background Clinically, various diseases cause myocardial ischemia (MI), which further
induces severe cardiac injury and leads to high mortality in patients. Ginsenoside Re, one of …