Decoding the genetic and epigenetic basis of asthma
Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
A pathogenic integrated view explaining the different endotypes of asthma and allergic disorders
The inflammation of allergic diseases is characterized by a complex interaction between
type 2 and type 3 immune responses, explaining clinical symptoms and histopathological …
type 2 and type 3 immune responses, explaining clinical symptoms and histopathological …
Toward a predict and prevent approach in obstructive airway diseases
S Couillard, N Petousi, KS Smigiel… - The Journal of Allergy and …, 2023 - Elsevier
Asthma and chronic obstructive pulmonary disease are currently diagnosed and treated
after the demonstration of variable airflow limitation and symptoms. Under this framework …
after the demonstration of variable airflow limitation and symptoms. Under this framework …
Revisiting asthma pharmacotherapy: where do we stand and where do we want to go?
M Cazzola, CP Page, MG Matera… - European …, 2023 - Eur Respiratory Soc
Several current guidelines/strategies outline a treatment approach to asthma, which
primarily consider the goals of improving lung function and quality of life and reducing …
primarily consider the goals of improving lung function and quality of life and reducing …
Paucigranulocytic asthma: potential pathogenetic mechanisms, clinical features and therapeutic management
AI Papaioannou, E Fouka, P Ntontsi… - Journal of Personalized …, 2022 - mdpi.com
Asthma is a heterogeneous disease usually characterized by chronic airway inflammation,
in which several phenotypes have been described, related to the age of onset, symptoms …
in which several phenotypes have been described, related to the age of onset, symptoms …
Type 2 low biomarker stability and exacerbations in severe uncontrolled asthma
A Viinanen, J Aakko, MI Lassenius, G Telg, K Nieminen… - Biomolecules, 2023 - mdpi.com
We investigated the stability of T2 low status, based on low levels of T2 biomarkers, and
exacerbation rates in T2 low and non-T2 low asthma from clinical retrospective data of …
exacerbation rates in T2 low and non-T2 low asthma from clinical retrospective data of …
Exhaled nitric oxide in asthma: from diagnosis to management
Summary FE NO demonstrated to be a noninvasive and very reproducible test,
encompassing many applications in the field of asthma management. Its routinely use …
encompassing many applications in the field of asthma management. Its routinely use …
Natural killer T cells in allergic asthma: implications for the development of novel immunotherapeutical strategies
C Gutiérrez-Vera, R García-Betancourt… - Frontiers in …, 2024 - frontiersin.org
Allergic asthma has emerged as a prevalent allergic disease worldwide, affecting most
prominently both young individuals and lower-income populations in developing and …
prominently both young individuals and lower-income populations in developing and …
The Dual Role of the Airway Epithelium in Asthma: Active Barrier and Regulator of Inflammation
Chronic airway inflammation is the cornerstone on which bronchial asthma arises, and in
turn, chronic inflammation arises from a complex interplay between environmental factors …
turn, chronic inflammation arises from a complex interplay between environmental factors …
Effects of biological therapies on patients with Type-2 high asthma and comorbid obesity
D Garg, LG Que, JL Ingram - Frontiers in Pharmacology, 2024 - frontiersin.org
Over 20 million adults and 6 million children in the United States (US) have asthma, a
chronic respiratory disease characterized by airway inflammation, bronchoconstriction, and …
chronic respiratory disease characterized by airway inflammation, bronchoconstriction, and …