Immune recognition occurs at specialized cell‐cell junctions when immune cells and target
cells physically touch. In this junction, groups of receptor‐ligand complexes assemble and …

B cell receptor (BCR)-mediated antigen-specific recognition activates B lymphocytes and
drives the humoral immune response. This enables the generation of antibody-producing …

Cells are highly dynamic and adopt variable shapes and sizes. These variations are
biologically important but challenging to investigate in a spatiotemporally controlled manner …

Mechanosensing, or how cells sense and respond to the physical environment, is crucial for
many aspects of biological function, ranging from cell movement during development to …

MAFLD stands for metabolic-related fatty liver disease, which is a prevalent liver disease
affecting one-third of adults worldwide, and is strongly associated with obesity …

Cells act as physical computational programs that utilize input signals to orchestrate
molecule-level protein–protein interactions (PPIs), generating and responding to forces …

The engagement of B cells with surface-tethered antigens triggers the formation of an
immune synapse (IS), where the local secretion of lysosomes can facilitate antigen uptake …

B cell antigen receptor (BCR) signaling induces actin cytoskeleton remodeling by
stimulating actin severing, actin polymerization, and the nucleation of branched actin …

We repurposed micropillar arrays to quantify spatiotemporal inter-adhesion communication.
Following the observation that integrin adhesions formed around pillar tops we relied on the …

Antigen-induced B-cell receptor (BCR) signaling is critical for initiating and regulating B-cell
activation. The actin cytoskeleton plays essential roles in BCR signaling. Upon encountering …