Validation of biomarkers of aging
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
[HTML][HTML] Radiographic Biomarkers for Knee Osteoarthritis: A Narrative Review
Conventional radiography remains the most widely available imaging modality in clinical
practice in knee osteoarthritis. Recent research has been carried out to develop novel …
practice in knee osteoarthritis. Recent research has been carried out to develop novel …
[HTML][HTML] The association between sleep parameters and sarcopenia in Japanese community-dwelling older adults
Purpose This study aimed to examine the association between sleep duration and quality
and sarcopenia, assessed by factors such as low muscle mass (LMM), low muscle strength …
and sarcopenia, assessed by factors such as low muscle mass (LMM), low muscle strength …
Integrated multicomponent interventions to support healthy aging of the whole person
HM Langevin, W Weber, W Chen - Aging Cell, 2024 - Wiley Online Library
Healthy aging is an integrated “whole person” process that involves an individual's biology,
behavior, and social/physical environment. With the recent development of antiaging drugs …
behavior, and social/physical environment. With the recent development of antiaging drugs …
[HTML][HTML] Magnesium and the Hallmarks of Aging
Magnesium is an essential ion in the human body that regulates numerous physiological
and pathological processes. Magnesium deficiency is very common in old age. Age-related …
and pathological processes. Magnesium deficiency is very common in old age. Age-related …
[HTML][HTML] Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop
Biologic aging reflects the genetic, molecular, and cellular changes underlying the
development of morbidity and mortality with advancing chronological age. As several …
development of morbidity and mortality with advancing chronological age. As several …
Geroscience-Centric Perspective for Geriatric Psychiatry: integrating aging biology with geriatric mental health research
The geroscience hypothesis asserts that physiological aging is caused by a small number of
biological pathways. Despite the explosion of geroscience research over the past couple of …
biological pathways. Despite the explosion of geroscience research over the past couple of …
[HTML][HTML] Human lifespan and sex-specific patterns of resilience to disease: a retrospective population-wide cohort study
J Sol, M Ortega-Bravo, M Portero-Otín, G Piñol-Ripoll… - BMC medicine, 2024 - Springer
Background Slower paces of aging are related to lower risk of developing diseases and
premature death. Therefore, the greatest challenge of modern societies is to ensure that the …
premature death. Therefore, the greatest challenge of modern societies is to ensure that the …
Metabolomic age and risk of 50 chronic diseases in community‐dwelling adults: A prospective cohort study
It is unclear how metabolomic age is associated with the risk of a wide range of chronic
diseases. Our analysis included 110,692 participants (training: n= 27,673; testing: n …
diseases. Our analysis included 110,692 participants (training: n= 27,673; testing: n …
[HTML][HTML] Effects of Human LAV-BPIFB4 Gene Therapy on the epigenetic clock and health of aged mice
ME Giuliani, V Barbi, G Bigossi, S Marcozzi… - International Journal of …, 2023 - mdpi.com
The homozygous genotype of the Longevity-Associated Variant (LAV) in Bactericidal/
Permeability-Increasing Fold-Containing Family B member 4 (BPIFB4) is enriched in long …
Permeability-Increasing Fold-Containing Family B member 4 (BPIFB4) is enriched in long …