Tucson children's respiratory study: 1980 to present

LM Taussig, AL Wright, CJ Holberg, M Halonen… - Journal of Allergy and …, 2003 - Elsevier
Continuing Medical Education examination The Tucson Children's Respiratory Study
(TCRS), begun in 1980, has followed 1246 subjects from birth together with their family …

Mycobacteria and other environmental organisms as immunomodulators for immunoregulatory disorders

GAW Rook, V Adams, J Hunt, R Palmer… - Springer seminars in …, 2004 - Springer
In the rich, developed parts of the world there has been a steady and simultaneous increase
in at least three groups of disease:(1) allergies,(2) inflammatory bowel diseases (IBD; eg …

Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy

MEH Bashir, S Louie, HN Shi… - The Journal of …, 2004 - journals.aai.org
The mechanisms by which signaling by the innate immune system controls susceptibility to
allergy are poorly understood. In this report, we show that intragastric administration of a …

Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease

G Tal, A Mandelberg, I Dalal, K Cesar… - The Journal of …, 2004 - academic.oup.com
Background. The clinical spectrum of respiratory syncytial virus (RSV) bronchiolitis in
previously healthy infants is extremely variable. Thus, it is likely that factors such as genetic …

Role of intestinal flora in the development of allergy

M Kalliomäki, E Isolauri - Current opinion in allergy and clinical …, 2003 - journals.lww.com
Role of intestinal flora in the development of allergy : Current Opinion in Allergy and Clinical
Immunology Role of intestinal flora in the development of allergy : Current Opinion in Allergy …

Endotoxin exposure, CD14, and allergic disease: an interaction between genes and the environment

A Simpson, SL John, F Jury, R Niven… - American journal of …, 2006 - atsjournals.org
Rationale: High endotoxin exposure may reduce the risk of allergic sensitization. Objective:
To determine the relationship between a promoter polymorphism in the CD14 gene (CD14 …

Endotoxin exposure in allergy and asthma: reconciling a paradox

AH Liu - Journal of Allergy and Clinical Immunology, 2002 - Elsevier
Well-established evidence links endotoxin exposure, especially in the workplace, to airways
disease. Endotoxin can increase disease severity by acting as a natural adjuvant to …

Toll-like receptors as potential therapeutic targets for multiple diseases

C Zuany-Amorim, J Hastewell, C Walker - Nature Reviews Drug …, 2002 - nature.com
The family of Toll-like receptors (TLRs) is receiving considerable attention as potential
regulators and controllers of the immune response through their ability to recognize …

Current insights into the genetics of food allergy

K Kanchan, S Clay, H Irizar, S Bunyavanich… - Journal of Allergy and …, 2021 - Elsevier
Food allergy (FA), a growing public health burden in the United States, and familial
aggregation studies support strong roles for both genes and environment in FA risk …

[图书][B] Aerosols handbook: measurement, dosimetry, and health effects

LS Ruzer, NH Harley - 2012 - books.google.com
With the rapid growth of the nanotechnology industry, the need to understand the biological
effects of aerosol exposure has become increasingly important. Featuring contributions by …