Principles and applications of nucleic acid strand displacement reactions

FC Simmel, B Yurke, HR Singh - Chemical reviews, 2019 - ACS Publications
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

Advanced photosensitizer activation strategies for smarter photodynamic therapy beacons

BM Luby, CD Walsh, G Zheng - … Chemie International Edition, 2019 - Wiley Online Library
Photodynamic therapy (PDT) is a clinical treatment in which a light‐absorbing drug called a
photosensitizer (PS) is combined with light and molecular oxygen to generate cytotoxic …

Self-assembling nucleic acid nanostructures functionalized with aptamers

A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Construction of a multiple-aptamer-based DNA logic device on live cell membranes via associative toehold activation for accurate cancer cell identification

X Chang, C Zhang, C Lv, Y Sun, M Zhang… - Journal of the …, 2019 - ACS Publications
The ability to accurately identify and isolate cells is the cornerstone of precise disease
diagnosis and therapies. A single-step cell identification method based on logic analysis of …

Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy

HM Meng, H Liu, H Kuai, R Peng, L Mo… - Chemical Society …, 2016 - pubs.rsc.org
The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …

DNA nanotechnology from the test tube to the cell

YJ Chen, B Groves, RA Muscat, G Seelig - Nature nanotechnology, 2015 - nature.com
Abstract The programmability of Watson–Crick base pairing, combined with a decrease in
the cost of synthesis, has made DNA a widely used material for the assembly of molecular …

Engineering a second‐order DNA logic‐gated nanorobot to sense and release on live cell membranes for multiplexed diagnosis and synergistic therapy

D Wang, S Li, Z Zhao, X Zhang… - Angewandte Chemie …, 2021 - Wiley Online Library
Tumor biomarker‐based theranostics have achieved broad interest and success in recent
years. However, single biomarker‐based recognition can cause false‐positive feedback …

The pathway to intelligence: using stimuli‐responsive materials as building blocks for constructing smart and functional systems

X Zhang, L Chen, KH Lim, S Gonuguntla… - Advanced …, 2019 - Wiley Online Library
Abstract Systems that are intelligent have the ability to sense their surroundings, analyze,
and respond accordingly. In nature, many biological systems are considered intelligent (eg …

Engineering a 3D DNA-logic gate nanomachine for bispecific recognition and computing on target cell surfaces

R Peng, X Zheng, Y Lyu, L Xu, X Zhang… - Journal of the …, 2018 - ACS Publications
Among the vast number of recognition molecules, DNA aptamers generated from cell-
SELEX exhibit unique properties for identifying cell membrane biomarkers, in particular …

Chemistry can make strict and fuzzy controls for bio-systems: DNA nanoarchitectonics and cell-macromolecular nanoarchitectonics

M Komiyama, K Yoshimoto, M Sisido… - Bulletin of the Chemical …, 2017 - academic.oup.com
In this review, we introduce two kinds of bio-related nanoarchitectonics, DNA
nanoarchitectonics and cell-macromolecular nanoarchitectonics, both of which are basically …