Nanocarrier vaccines for respiratory infections

Y Jiang, L Lei, M Zhao, Y Tian, Y Huang… - Trends in Molecular …, 2025 - cell.com
Respiratory infections continue to pose a major global health challenge, leading to high
morbidity and mortality. Effective vaccines are crucial for prevention of these, and …

Engineered probiotic Escherichia coli elicits immediate and long-term protection against influenza A virus in mice

L Huang, W Tang, L He, M Li, X Lin, A Hu… - Nature …, 2024 - nature.com
Influenza virus infection remains a major global health problem and requires a universal
vaccine with broad protection against different subtypes as well as a rapid-response vaccine …

Nanoparticle targeting cGAS-STING signaling in disease therapy

L Zhou, Y Huang, Y Wu, S Tang - Nano Research, 2024 - Springer
The cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of
interferon (IFN) genes (cGAS-STING) signaling pathway is crucial for sensing abnormal …

A novel “prime and pull” strategy mediated by the combination of two dendritic cell-targeting designs induced protective lung tissue-resident memory T cells against …

Z Wang, Y He, W Wang, Y Tian, C Ge, F Jia… - Journal of …, 2023 - Springer
Vaccination is still the most promising strategy for combating influenza virus pandemics.
However, the highly variable characteristics of influenza virus make it difficult to develop …

Single-component multilayered self-assembling protein nanoparticles displaying extracellular domains of matrix protein 2 as a pan-influenza A vaccine

K Braz Gomes, YN Zhang, YZ Lee, M Eldad, A Lim… - ACS …, 2023 - ACS Publications
The development of a cross-protective pan-influenza A vaccine remains a significant
challenge. In this study, we designed and evaluated single-component self-assembling …

[HTML][HTML] A Single-Component Multilayered Self-Assembling Protein Nanoparticle Vaccine Based on Extracellular Domains of Matrix Protein 2 against Both Influenza A …

YN Zhang, KB Gomes, YZ Lee, G Ward, B Xie… - Vaccines, 2024 - mdpi.com
The development of an effective and broadly protective influenza vaccine against circulating
and emerging strains remains elusive. In this study, we evaluated a potentially universal …

Vectorisation d'antigènes d'intérêt par des nanoparticules lipidiques pour application vaccinale

L Bourlon - 2023 - theses.hal.science
Les vaccins antigrippaux sont considérés comme la mesure la plus efficace pour prévenir la
grippe. Ils se basent sur l'utilisation de l'hémagglutinine (HA) en tant qu'antigène. Cette …

[PDF][PDF] Single-Component Multilayered Self-Assembling Protein Nanoparticles Displaying Extracellular Domains of Matrix Protein 2 as

A Pan-influenza - 2023 - jzhulab.org
The development of a cross-protective paninfluenza A vaccine remains a significant
challenge. In this study, we designed and evaluated single-component selfassembling …