Challenges and approaches to predicting RNA with multiple functional structures
SJ Schroeder - Rna, 2018 - rnajournal.cshlp.org
The revolution in sequencing technology demands new tools to interpret the genetic code.
As in vivo transcriptome-wide chemical probing techniques advance, new challenges …
As in vivo transcriptome-wide chemical probing techniques advance, new challenges …
A systematic search for RNA structural switches across the human transcriptome
RNA structural switches are key regulators of gene expression in bacteria, but their
characterization in Metazoa remains limited. Here, we present SwitchSeeker, a …
characterization in Metazoa remains limited. Here, we present SwitchSeeker, a …
Uncovering the folding landscape of RNA secondary structure using deep graph embeddings
Biomolecular graph analysis has recently gained much attention in the emerging field of
geometric deep learning. Here we focus on organizing biomolecular graphs in ways that …
geometric deep learning. Here we focus on organizing biomolecular graphs in ways that …
Uncovering the folding landscape of RNA secondary structure with deep graph embeddings
Biomolecular graph analysis has recently gained much attention in the emerging field of
geometric deep learning. Here we focus on organizing biomolecular graphs in ways that …
geometric deep learning. Here we focus on organizing biomolecular graphs in ways that …
Local RNA folding revisited
Most of the functional RNA elements located within large transcripts are local. Local folding
therefore serves a practically useful approximation to global structure prediction. Due to the …
therefore serves a practically useful approximation to global structure prediction. Due to the …
Base-pair ambiguity and the kinetics of RNA folding
Background A folding RNA molecule encounters multiple opportunities to form non-native
yet energetically favorable pairings of nucleotide sequences. Given this forbidding free …
yet energetically favorable pairings of nucleotide sequences. Given this forbidding free …
The Structural Determination of Viral RNA Elements Using Chaperone Assisted RNA Crystallography
CA Roman - 2021 - search.proquest.com
RNA is an incredibly diverse molecule, simultaneously encoding for proteins and adopting
tertiary structures capable of recruiting macromolecular components, binding ligands and …
tertiary structures capable of recruiting macromolecular components, binding ligands and …
Base-pair Ambiguity and the Kinetics of RNA Folding: a Hypothesis-Driven Statistical Analysis
Non-coding RNA molecules contribute to cellular function through diverse roles, including
genome regulation, DNA and RNA repair, RNA splicing, catalysis, protein synthesis, and …
genome regulation, DNA and RNA repair, RNA splicing, catalysis, protein synthesis, and …