[HTML][HTML] A review of the berberine natural polysaccharide nanostructures as potential anticancer and antibacterial agents

S Khan, A Hussain, F Attar, SH Bloukh, Z Edis… - Biomedicine & …, 2022 - Elsevier
Despite the promising medicinal properties, berberine (BBR), due to its relatively poor
solubility in plasma, low bio-stability and limited bioavailability is not used broadly in clinical …

Coumarins derivatives and inflammation: Review of their effects on the inflammatory signaling pathways

B Rostom, R Karaky, I Kassab, MSI Veitía - European Journal of …, 2022 - Elsevier
Natural and synthetic coumarins have been extensively described in the literature as
effective drugs with several pharmacological activities. Many valuable publications have …

Plant secondary metabolites: an introduction of their chemistry and biological significance with physicochemical aspect

A Sharma, S Sharma, A Kumar, V Kumar… - … -chemical properties and …, 2022 - Springer
Nature is the immense source of chemical compounds or substances usually acknowledged
as natural products. Plants are the considerable source of an inestimable diversity of natural …

Coumarins as versatile therapeutic phytomolecules: A systematic review

MK Hussain, S Khatoon, MF Khan, MS Akhtar… - Phytomedicine, 2024 - Elsevier
Background Coumarins, abundantly distributed in a plethora of biologically active
compounds, serve as a fundamental motif in numerous natural products, drugs, and …

Research advances in lotus leaf as Chinese dietary herbal medicine

H Zheng, L Han, W Shi, X Fang, Y Hong… - The American journal of …, 2022 - World Scientific
Lotus leaf (Heye), the dry foliage of Nelumbo nucifera Gaertn, has been valuable as a
dietary herbal medicine for thousands of years. Phytochemical studies indicated that …

A double responsive fluorescent platform for sensing heavy metal ions based on a dual-emitting fluorescent covalent organic framework hydrogel film

Y Jia, J Wang, L Zhao, B Yan - Dalton Transactions, 2022 - pubs.rsc.org
A new luminescent hybrid material with dual-emission centers (Eu@ Dye@ TpDq hydrogel)
based on a covalent organic framework (COF) has been successfully prepared. First, we …

Cinnamon and its active compounds: A potential candidate in disease and tumour management through modulating various genes activity

SA Almatroodi, MA Alsahli, A Almatroudi, S Anwar… - Gene Reports, 2020 - Elsevier
Free radicals and other reactive oxygen species have been reported to be implicated in the
pathology of several human diseases. Therefore, the supplementation of anti-oxidizing …

Isatin conjugates as antibacterial agents: a brief review

F Hassan, I Azad, M Asif, D Shukla… - Medicinal …, 2023 - ingentaconnect.com
Pathogenic bacteria, with their innate resistance to drugs, pose a constant threat to human
health and well-being and put a persistent strain on the health care system. Development of …

Fragment-based design and synthesis of coumarin-based thiazoles as dual c-MET/STAT-3 inhibitors for potential antitumor agents

BH Naguib, HA Elsebaie, MS Nafie, S Mohamady… - Bioorganic …, 2024 - Elsevier
Abstract c-MET and STAT-3 are significant targets for cancer treatments. Here, we describe
a class of very effective dual STAT-3 and c-MET inhibitors with coumarin-based thiazoles …

In-silico identification and exploration of small molecule coumarin-1, 2, 3-triazole hybrids as potential EGFR inhibitors for targeting lung cancer

S Kumar, I Ali, F Abbas, F Shafiq, AK Yadav… - Molecular Diversity, 2024 - Springer
Globally, lung cancer is a significant public health concern due to its role as the leading
cause of cancer-related mortalities. The promising target of EGFR for lung cancer treatment …