Abstract mRNA-Lipid nanoparticles (LNPs) are at the forefront of global medical research.
With the development of mRNA-LNP vaccines to combat the COVID-19 pandemic, the …

The development of therapeutic approaches for the induction of robust, long-lasting and
antigen-specific immune tolerance remains an important unmet clinical need for the …

Abstract Atezolizumab (anti-PD-L1) combined with bevacizumab (anti-VEGFA) is the first-
line immunotherapy for advanced hepatocellular carcinoma (HCC), but the number of …

Dendritic cells (DCs) are myeloid cells bridging the innate and adaptive immune system. By
cross‐presenting tumor‐associated antigens (TAAs) liberated upon spontaneous or therapy …

Conventional dendritic cells (DCs) are essential mediators of antitumor immunity. As a
result, cancers have developed poorly understood mechanisms to render DCs dysfunctional …

Conventional dendritic cells (cDCs) generate protective cytotoxic T lymphocyte (CTL)
responses against extracellular pathogens and tumors. This is achieved through a process …

Dendritic cells (DCs) are crucial gatekeepers of the balance between immunity and
tolerance. They exist in two functional states, immature or mature, that refer to an information …

The efficient activation of professional antigen‐presenting cells—such as dendritic cells
(DC)—in tumors and lymph nodes is critical for the design of next‐generation cancer …

Oral tolerance is the process by which feeding of soluble proteins induces antigen-specific
systemic immune unresponsiveness. Oral tolerance is thought to have a central role in …

Cellular metabolism modulates dendritic cell (DC) maturation and activation. Migratory
dendritic cells (mig-DCs) travelling from the tissues to draining lymph nodes (dLNs) are …