Ribosome biogenesis and protein synthesis are fundamental rate-limiting steps for cell
growth and proliferation. The ribosomal proteins (RPs), comprising the structural parts of the …

Although ribosomal proteins are known for playing an essential role in ribosome assembly
and protein translation, their ribosome-independent functions have also been greatly …

With advances in genomic sequencing technology, the number of reported gene-disease
relationships has rapidly expanded. However, the evidence supporting these claims varies …

Ribosomal RNAs are the most abundant and universal noncoding RNAs in living organisms.
In eukaryotes, three of the four ribosomal RNAs forming the 40S and 60S subunits are borne …

Regulation of mRNA translation offers the opportunity to diversify the expression and
abundance of proteins made from individual gene products in cells, tissues and organisms …

Ribosomes play a pivotal role in the molecular life of every cell. Moreover, synthesis of
ribosomes is one of the most energetically demanding of all cellular processes. In eukaryotic …

A veritable explosion of primary research papers within the past 10 years focuses on
nucleolar and ribosomal stress, and for good reason: with ribosome biosynthesis …

Anemia is a major source of morbidity and mortality worldwide. Here we review recent
insights into how red blood cells (RBCs) are produced, the pathogenic mechanisms …

Mutations that target the ubiquitous process of ribosome assembly paradoxically cause
diverse tissue-specific disorders (ribosomopathies) that are often associated with an …

Ribosomes are essential components of the protein synthesis machinery. The process of
ribosome biogenesis is well organized and tightly regulated. Recent studies have shown …