Dopamine (DA) receptor, a significant G protein-coupled receptor, is classified into two
families: D1-like (D1 and D5) and D2-like (D2, D3, and D4) receptor families, with further …

Although histamine H3 receptors are predominantly known as presynaptic receptors,
regulating the release of neurotransmitters such as dopamine, acetylcholine, and histamine …

Background: The histamine-3 receptor (H3R) is an auto-and heteroreceptor that inhibits the
release of histamine and other neurotransmitters. Post-mortem evidence has found altered …

Tic disorders affect~ 5% of the population and are frequently comorbid with obsessive-
compulsive disorder, autism, and attention deficit disorder. Histamine dysregulation has …

While the normal functions of histamine (HA) in the central nervous system have gradually
come into focus over the past 30 years, the relationship of abnormalities in neurotransmitter …

Rationale The rewarding effect of Methamphetamine (METH) is commonly believed to play
an important role in METH use disorder. The altered expression of dopamine D1 receptor …

Histaminergic dysfunction has been recently linked to tic disorders and to aberrant striatal
function. There is a particular interest in the histamine 3 receptor (H3R) due to its clinical …

Parkinson's disease is associated with the loss of more than 40% of dopaminergic neurons
in the substantia nigra pars compacta. One of the therapeutic options for restoring striatal …

Alcohol use disorder (AUD) is a severe, yet not fully understood, mental health problem. It is
associated with liver, pancreatic, and gastrointestinal diseases, thereby highly increasing …

We studied the effect of activating histamine H 3 receptors (H 3 Rs) on rat nucleus
accumbens (rNAcc) dopaminergic transmission by analyzing [3 H]-dopamine uptake by …