Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review

A Sosnik, J das Neves, B Sarmento - Progress in Polymer Science, 2014 - Elsevier
The presence of a mucus layer that covers the surface of a variety of organs has been
capitalized to develop mucoadhesive dosage forms that remain in the administration site for …

Cilia dysfunction in lung disease

AE Tilley, MS Walters, R Shaykhiev… - Annual review of …, 2015 - annualreviews.org
A characteristic feature of the human airway epithelium is the presence of ciliated cells
bearing motile cilia, specialized cell surface projections containing axonemes composed of …

Ionic liquid-based formulation approaches for enhanced transmucosal drug delivery

O Khan, R Bhawale, R Vasave, NK Mehra - Drug Discovery Today, 2024 - Elsevier
Highlights•ILs, a potential approach for improving physico-chemical and biological
properties of APIs.•Mucus membranes serves as a barrier for drug delivery.•Choline-based …

[HTML][HTML] The mucoadhesive nanoparticle-based delivery system in the development of mucosal vaccines

K Zhao, Y Xie, X Lin, W Xu - International Journal of Nanomedicine, 2022 - ncbi.nlm.nih.gov
Mucosal tissue constitutes the largest interface between the body and the external
environment, regulating the entry of pathogens, particles, and molecules. Mucosal …

Molecular and cellular cues governing nanomaterial–mucosae interactions: from nanomedicine to nanotoxicology

J das Neves, RS Arzi, A Sosnik - Chemical Society Reviews, 2020 - pubs.rsc.org
Mucosal tissues constitute the largest interface between the body and the surrounding
environment and they regulate the access of molecules, supramolecular structures …

Acquired CFTR dysfunction in chronic bronchitis and other diseases of mucus clearance

SV Raju, GM Solomon, MT Dransfield… - Clinics in chest …, 2015 - pmc.ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) is a major public health problem accounting
for more than 100,000 deaths and 750,000 hospitalizations each year in the United States …

Nasal mucociliary clearance in smokers: a systematic review

A Prasetyo, U Sadhana… - International Archives of …, 2021 - thieme-connect.com
Introduction Smoking is one of the most important causes of mortality and morbidity in the
world, as it is related to the risk factor and etiology of respiratory-tract diseases. Long-term …

[HTML][HTML] The effects of smoking and smoking cessation on nasal mucociliary clearance, mucus properties and inflammation

DMO Utiyama, CT Yoshida, DM Goto… - Clinics, 2016 - SciELO Brasil
OBJECTIVE: The aim of the present study was to assess nasal mucociliary clearance,
mucus properties and inflammation in smokers and subjects enrolled in a Smoking …

[PDF][PDF] How does electronic cigarette smoking affect sinonasal symptoms and nasal mucociliary clearance

TL Kumral, Z Saltürk, G Yildirim, Y Uyar, G Berkiten… - B-ent, 2016 - b-ent.be
How does electronic cigarette smoking affect sinonasal symptoms and nasal mucociliary
clearance? Objective: is to evaluate the sinonasal symptom scores and mucociliary …