Chagas disease is a neglected tropical disease, which affects an estimate of 6‐7 million
people worldwide. Chagas disease is caused by Trypanosoma cruzi, which is a eukaryotic …

Trypanosoma cruzi, the causative agent of Chagas disease, is an obligatory intracellular
parasite with a digenetic life cycle. Due to the variety of host environments, it faces several …

Leishmaniasis is one of the six diseases regarded most neglected by World Health
Organization which is predominant in developing countries. Clinically, among the different …

The toxicity of oxygen and nitrogen reactive species appears to be merely the tip of the
iceberg in the world of redox homeostasis. Now, oxidative stress can be seen as a two-sided …

The molecular repertoire of Trypanosoma cruzi effects its virulence and impacts the clinical
course of the resulting Chagas disease. This study aimed to determine the mechanism …

Trypanothione is a unique and essential redox metabolite of trypanosomatid parasites, the
biosynthetic pathway of which is regarded as a promising target for antiparasitic drugs …

Chagas Disease, African sleeping sickness, and leishmaniasis are neglected diseases
caused by pathogenic trypanosomatid parasites, which have a considerable impact on …

Background: The American trypanosomiasis, Chagas disease, is a parasitic infection
typically spread by triatomine vectors affecting millions of people all over Latin America …

Leishmania is a unicellular protozoan parasite which causes leishmaniasis, a neglected
tropical disease. It possess a unique thiol metabolism comprising of several proteins among …

There is an urgent need to develop new treatments for Chagas' disease. To identify drug
targets, it is important to understand the basic biology of Trypanosoma cruzi, in particular …