Management of stroke in neonates and children: a scientific statement from the American Heart Association/American Stroke Association

DM Ferriero, HJ Fullerton, TJ Bernard, L Billinghurst… - Stroke, 2019 - Am Heart Assoc
Purpose—Much has transpired since the last scientific statement on pediatric stroke was
published 10 years ago. Although stroke has long been recognized as an adult health …

Childhood stroke

PB Sporns, HJ Fullerton, S Lee, H Kim, WD Lo… - Nature Reviews …, 2022 - nature.com
Stroke is an important cause of neurological morbidity in children; most survivors have
permanent neurological deficits that affect the remainder of their life. Stroke in childhood, the …

Feasibility, safety, and outcome of endovascular recanalization in childhood stroke: the Save ChildS Study

PB Sporns, R Sträter, J Minnerup, H Wiendl… - JAMA …, 2020 - jamanetwork.com
Importance Randomized clinical trials have shown the efficacy of thrombectomy of large
intracranial vessel occlusions in adults; however, any association of therapy with clinical …

[HTML][HTML] Neonatal brain injuries in England: population-based incidence derived from routinely recorded clinical data held in the National Neonatal Research …

C Gale, Y Statnikov, S Jawad, SN Uthaya… - Archives of Disease in …, 2018 - fn.bmj.com
Objective In 2015, the Department of Health in England announced an ambition to reduce
'brain injuries occurring during or soon after birth'. We describe the development of a …

Predicting recovery and outcome after pediatric stroke: results from the international pediatric stroke study

RJ Felling, MF Rafay, TJ Bernard… - Annals of …, 2020 - Wiley Online Library
Objective To characterize predictors of recovery and outcome following pediatric arterial
ischemic stroke, hypothesizing that age influences recovery after stroke. Methods We …

Australian clinical consensus guideline: the diagnosis and acute management of childhood stroke

TL Medley, C Miteff, I Andrews, T Ware… - … Journal of Stroke, 2019 - journals.sagepub.com
Stroke is among the top 10 causes of death in children and survivors carry resulting
disabilities for decades, at substantial cost to themselves and their families. Children are not …

Mechanical thrombectomy in pediatric stroke: systematic review, individual patient data meta-analysis, and case series

K Bhatia, H Kortman, C Blair, G Parker… - Journal of …, 2019 - thejns.org
OBJECTIVE The role of mechanical thrombectomy in pediatric acute ischemic stroke is
uncertain, despite extensive evidence of benefit in adults. The existing literature consists of …

Cerebral ischemia in the developing brain

RM Dietz, AL Dingman… - Journal of Cerebral Blood …, 2022 - journals.sagepub.com
Brain ischemia affects all ages, from neonates to the elderly population, and is a leading
cause of mortality and morbidity. Multiple preclinical rodent models involving different ages …

Reduced microglia activation following metformin administration or microglia ablation is sufficient to prevent functional deficits in a mouse model of neonatal stroke

C Bourget, KV Adams, CM Morshead - Journal of Neuroinflammation, 2022 - Springer
Background Neonatal stroke is a devastating insult that can lead to life-long impairments. In
response to hypoxic–ischaemic injury, there is loss of neurons and glia as well as a …

Acute ischemic stroke in childhood: a comprehensive review

M Mastrangelo, L Giordo, G Ricciardi… - European Journal of …, 2022 - Springer
This review provides an updated analysis of the main aspects involving the diagnosis and
the management of children with acute ischemic stroke. Acute ischemic stroke is an …