[HTML][HTML] The role of intolerance of uncertainty in classical threat conditioning: Recent developments and directions for future research

J Morriss, DV Zuj, G Mertens - International Journal of Psychophysiology, 2021 - Elsevier
Intolerance of uncertainty (IU), the tendency to find uncertainty aversive, is an important
transdiagnostic dimension in mental health disorders. Over the last decade, there has been …

Pattern analysis of neuroimaging data reveals novel insights on threat learning and extinction in humans

AC Hennings, SE Cooper, JA Lewis-Peacock… - Neuroscience & …, 2022 - Elsevier
Several decades of rodent neurobiology research have identified a network of brain regions
that support Pavlovian threat conditioning and extinction, focused predominately on the …

Temporally and anatomically specific contributions of the human amygdala to threat and safety learning

Z Wen, CM Raio, EF Pace-Schott… - Proceedings of the …, 2022 - National Acad Sciences
Neural plasticity in subareas of the rodent amygdala is widely known to be essential for
Pavlovian threat conditioning and safety learning. However, less consistent results have …

Anxiety and the neurobiology of temporally uncertain threat anticipation

J Hur, JF Smith, KA DeYoung… - Journal of …, 2020 - Soc Neuroscience
When extreme, anxiety—a state of distress and arousal prototypically evoked by uncertain
danger—can be debilitating. Uncertain anticipation is a shared feature of situations that elicit …

Robust BOLD responses to faces but not to conditioned threat: challenging the amygdala's reputation in human fear and extinction learning

RM Visser, J Bathelt, HS Scholte… - Journal of …, 2021 - Soc Neuroscience
Most of our knowledge about human emotional memory comes from animal research. Based
on this work, the amygdala is often labeled the brain's “fear center”, but it is unclear to what …

[HTML][HTML] I doubt it is safe: A meta-analysis of self-reported intolerance of uncertainty and threat extinction training

J Morriss, S Wake, C Elizabeth… - … Psychiatry Global Open …, 2021 - Elsevier
Background Intolerance of uncertainty (IU), the tendency to find uncertainty distressing, is an
important transdiagnostic dimension in mental health disorders. Higher self-reported IU has …

Pavlovian safety learning: An integrative theoretical review

PAF Laing, B Vervliet, JE Dunsmoor… - Psychonomic Bulletin & …, 2024 - Springer
Safety learning involves associating stimuli with the absence of threats, enabling the
inhibition of fear and anxiety. Despite growing interest in psychology, psychiatry, and …

Trait anxiety is associated with hidden state inference during aversive reversal learning

O Zika, K Wiech, A Reinecke, M Browning… - Nature …, 2023 - nature.com
Updating beliefs in changing environments can be driven by gradually adapting
expectations or by relying on inferred hidden states (ie contexts), and changes therein …

How representative are neuroimaging samples? Large-scale evidence for trait anxiety differences between fMRI and behaviour-only research participants

CJ Charpentier, P Faulkner, ER Pool… - Social cognitive and …, 2021 - academic.oup.com
Over the past three decades, functional magnetic resonance imaging (fMRI) has become
crucial to study how cognitive processes are implemented in the human brain. However, the …

[HTML][HTML] Unconditioned stimulus devaluation decreases the generalization of costly safety behaviors

AHK Wong, M Franzen, MJ Wieser - Journal of Anxiety Disorders, 2024 - Elsevier
Safety behaviors are often maladaptive in clinical anxiety as they typically persist without
realistic threat and cause various impairments. In the laboratory, safety behaviors are …