Background Cardiogenic shock (CS) and low cardiac output syndrome (LCOS) as
complications of acute myocardial infarction (AMI), heart failure (HF) or cardiac surgery are …

Background Inotropes and vasopressors are frequently administered to critically ill patients
in order to improve haemodynamic function and restore adequate organ perfusion …

Background Levosimendan has been shown to confer direct renoprotection in renal
endotoxemic and ischemia-reperfusion injury and could increase renal blood flow in …

Objectives Low cardiac output syndrome (LCOS) is a serious complication after cardiac
surgery. Despite scientific interest in LCOS, there is no uniform definition used in current …

Background Cardiogenic shock (CS) and low cardiac output syndrome (LCOS) are
potentially life‐threatening complications of acute myocardial infarction (AMI), heart failure …

Background Previous studies have shown beneficial effects of levosimendan in high-risk
patients undergoing cardiac surgery. Two large randomized controlled trials (RCTs) …

Background Inodilators are commonly used in critically ill patients, but their effect on survival
has not been properly studied to date. The objective of this work was to conduct a network …

Acute kidney injury is one of the most common major complications of cardiac surgery and it
is associated with increased morbidity and mortality. Cardiac surgery-associated acute …

Background There has been conflicting evidence concerning the effect of levosimendan on
clinical outcomes in patients undergoing cardiac surgery. Therefore, we performed a …

Background Several studies suggested beneficial effects of perioperative levosimendan on
postoperative outcome after cardiac surgery. However, three large randomized controlled …