Cytotoxic properties of 1, 3, 4-thiadiazole derivatives—A review

S Janowska, A Paneth, M Wujec - Molecules, 2020 - mdpi.com
During recent years, small molecules containing five-member heterocyclic moieties have
become the subject of considerable growing interest for designing new antitumor agents …

1, 3, 4-thiadiazole: A privileged scaffold for drug design and development

X Han, YL Yu, YS Hu, XH Liu - Current Topics in Medicinal …, 2021 - ingentaconnect.com
1, 3, 4-thiadiazole is a five-membered aromatic heterocycle containing two nitrogen atoms
and one sulfur atom. As a privileged scaffold, it has its unique chemical properties and …

Spectroscopic and theoretical investigation into substituent-and aggregation-related dual fluorescence effects in the selected 2-amino-1, 3, 4-thiadiazoles

I Budziak, D Karcz, M Makowski… - Journal of Molecular …, 2019 - Elsevier
The article presents the results of spectroscopic studies conducted on three compounds
from the 1, 3, 4-thiadiazole group: 2-amino-5-phenyl-1, 3, 4-thiadiazole (TB), 2-amino-5-(2 …

[HTML][HTML] Synthesis of β-carboline fatty alcohol hybrid molecules and characterization of their biological and antioxidant activities

V Kontham, B Ippakayala, D Madhu - Arabian Journal of Chemistry, 2021 - Elsevier
Nine new β-carboline fatty alcohol hybrids were synthesized from natural amino acid L-
tryptophan by the conjugation of 10-undecen-1-ol via ester linkage. All the synthesized …

Synthesis, antimicrobial and cytotoxicity studies of novel undecenoic acid-based triazolothiadiazole derivatives

V Venepally, K Sirisha, CG Kumar, EV Krishna… - 2022 - nopr.niscpr.res.in
In the present study, synthesis, antimicrobial and cytotoxic activity studies of 3, 6-
disubstituted-[1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazole series compounds have been …