The endoplasmic reticulum (ER) is an intracellular organelle that fosters the correct folding
of linear polypeptides and proteins, a process tightly governed by the ER‐resident enzymes …

Nonalcoholic fatty liver disease (NAFLD) defines fat accumulation in the liver, and it is
commonly associated with metabolic syndromes like diabetes and obesity. Progressive …

Abstract Sestrin2 (SESN2), a highly conserved stress-responsive protein, can be triggered
by various noxious stimuli, such as hypoxia, DNA damage, oxidative stress, endoplasmic …

Obesity challenges lipid and carbohydrate metabolism. The resulting glucolipotoxicity
causes endoplasmic reticulum (ER) dysfunction, provoking the accumulation of immature …

Background Dietary polyphenol treatment of non-alcoholic fatty liver disease (NAFLD) is a
novel direction, and the existing clinical studies have little effective evidence for its …

Fatty liver disease (FLD), including nonalcoholic fatty liver disease (NAFLD) and alcoholic
fatty liver disease (AFLD), is a serious chronic metabolic disease that affects a wide range of …

The global incidence rate of non-alcoholic fatty liver disease (NAFLD) is approximately 25%.
With the global increase in obesity and its associated metabolic syndromes, NAFLD has …

Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-dysfunction-
associated fatty liver disease (MAFLD), affects a quarter of the worldwide population. Natural …

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
world, and its incidence continues to increase each year. Yet, there is still no definitive drug …

TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR 1 and 2 (TCP)
family proteins are the plant-specific transcription factors extensively participating in diverse …