The regulation of cyclins and cyclin-dependent kinases in the development of gastric cancer

A Javed, M Yarmohammadi, KS Korkmaz… - International Journal of …, 2023 - mdpi.com
Gastric cancer predominantly occurs in adenocarcinoma form and is characterized by
uncontrolled growth and metastases of gastric epithelial cells. The growth of gastric cells is …

Annexin A4 and cancer

B Wei, C Guo, S Liu, MZ Sun - Clinica chimica acta, 2015 - Elsevier
Abstract Annexin A4 (Anxa4) is one of the Ca 2+-regulated and phospholipid-binding
annexin superfamily proteins. Anxa4 has a potential role in diagnosis, prognosis, and …

ANXA4 promotes trophoblast invasion via the PI3K/Akt/eNOS pathway in preeclampsia

Y Xu, L Sui, B Qiu, X Yin, J Liu… - American Journal of …, 2019 - journals.physiology.org
The inadequate trophoblast invasion is associated with the development of preeclampsia
(PE). Considering that annexin A4 (ANXA4) enhances tumor invasion, we aimed to explore …

Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population

CA Haiman, Y Han, Y Feng, L Xia, C Hsu… - PLoS …, 2013 - journals.plos.org
Rare variation in protein coding sequence is poorly captured by GWAS arrays and has been
hypothesized to contribute to disease heritability. Using the Illumina HumanExome SNP …

Inhibition of Renin Expression Is Regulated by an Epigenetic Switch From an Active to a Poised State

JP Smith, R Paxton, S Medrano, NC Sheffield… - …, 2024 - ahajournals.org
BACKGROUND: Renin-expressing cells are myoendocrine cells crucial for the maintenance
of homeostasis. Renin is regulated by cAMP, p300 (histone acetyltransferase p300)/CBP …

Analysis of gastric cancer transcriptome allows the identification of histotype specific molecular signatures with prognostic potential

A Carino, L Graziosi, S Marchianò, M Biagioli… - Frontiers in …, 2021 - frontiersin.org
Gastric cancer is the fifth most common malignancy but the third leading cause of cancer-
associated mortality worldwide. Therapy for gastric cancer remain largely suboptimal …

[HTML][HTML] Overexpression of HS6ST2 is associated with poor prognosis in patients with gastric cancer

Y Jin, J He, J Du, RX Zhang, HB Yao… - Oncology …, 2017 - spandidos-publications.com
The purpose of the present study was to investigate the clinical significance of the
expression of heparan sulfate 6‑O‑sulfotransferase 2 (HS6ST2) in gastric cancer (GC). The …

Annexin A4 is involved in proliferation, chemo-resistance and migration and invasion in ovarian clear cell adenocarcinoma cells

T Mogami, N Yokota, M Asai-Sato, R Yamada… - PloS one, 2013 - journals.plos.org
Ovarian clear cell adenocarcinoma (CCC) is the second most common subtype of ovarian
cancer after high-grade serous adenocarcinomas. CCC tends to develop resistance to the …

Role of annexin A family in tumorigenesis and chemoresistance of gastric cancer.

Z Rong-Rong, MAO Xiao-Rong, W Xiao-Feng… - …, 2022 - search.ebscohost.com
Gastric cancer (GC) is one of the most common cancer types and the fourth leading cause of
cancer-related mortality among all malignant tumors worldwide. Due to insidious onset and …

Directional Secretomes Reflect Polarity-Specific Functions in an In Vitro Model of Human Bronchial Epithelium

DK Pillai, BJV Sankoorikal, E Johnson… - American journal of …, 2014 - atsjournals.org
The polarity of the conducting airway epithelium is responsible for its directional secretion.
This is an essential characteristic of lung integrity and function that dictates interactions …