Revolutionizing brain interventions: the multifaceted potential of histotripsy

Y Verma, AS Perera Molligoda Arachchige - Neurosurgical Review, 2024 - Springer
Histotripsy, a non-thermal ultrasound technique, holds significant promise in various
applications within the realm of brain interventions. While its use for treating brain tumors is …

Cell mechanics regulate the migration and invasion of hepatocellular carcinoma cells via JNK signaling

J Wang, B Zhang, X Chen, Y Xin, K Li, C Zhang… - Acta biomaterialia, 2024 - Elsevier
Hepatocellular carcinoma (HCC) cells, especially those with metastatic competence, show
reduced stiffness compared to the non-malignant counterparts. However, it is still unclear …

The influence of viscosity of hydrogels on the spreading and migration of cells in 3D bioprinted skin cancer models

LH Du Plessis, C Gouws, D Nieto - Frontiers in Cell and …, 2024 - frontiersin.org
Various in vitro three-dimensional (3D) tissue culture models of human and diseased skin
exist. Nevertheless, there is still room for the development and improvement of 3D bioprinted …

Circulating tumor cells with metastasis-initiating competence survive fluid shear stress during hematogenous dissemination through CXCR4-PI3K/AKT signaling

Y Xin, B Hu, K Li, G Hu, C Zhang, X Chen, K Tang… - Cancer Letters, 2024 - Elsevier
To seed lethal secondary lesions, circulating tumor cells (CTCs) must survive all rate-limiting
factors during hematogenous dissemination, including fluid shear stress (FSS) that poses a …

High‐Sensitive Spatiotemporal Distribution Imaging of Compression Stresses Based on Time‐Evolutional Responsiveness

N Ono, R Seishima, K Shigeta, K Okabayashi, H Imai… - Small, 2024 - Wiley Online Library
Mechanoresponsive materials have been studied to visualize and measure stresses in
various fields. However, the high‐sensitive and spatiotemporal imaging remain a …

[HTML][HTML] Phenotypic Heterogeneity, Bidirectionality, Universal Cues, Plasticity, Mechanics, and the Tumor Microenvironment Drive Cancer Metastasis

CT Mierke - Biomolecules, 2024 - mdpi.com
Tumor diseases become a huge problem when they embark on a path that advances to
malignancy, such as the process of metastasis. Cancer metastasis has been thoroughly …

[HTML][HTML] Atomic Force Microscopy for the Study of Cell Mechanics in Pharmaceutics

H Siboni, I Ruseska, A Zimmer - Pharmaceutics, 2024 - mdpi.com
Cell mechanics is gaining attraction in drug screening, but the applicable methods have not
yet become part of the standardized norm. This review presents the current state of the art for …

Pore-scale viscous fingering as a mechanism for pattern formation–a historical overview, application, and the ways of controlling it

I Cvetkovic, S Milicev - Advances in Physics: X, 2024 - Taylor & Francis
Viscous fingering instability, as one of the numerous fluid instabilities and mechanisms of
pattern formation, is very common in different fields of research. First studied experimentally …

The impact of choledochal cysts on bile fluid dynamics: A perspective using computational fluid dynamics and surface mapping technique

X Li, X Ni, W Sun, J Liu, Y Shang, H Liu, J Tu - Physics of Fluids, 2024 - pubs.aip.org
Choledochal cysts (CCs) are an important risk factor for cholangiocarcinoma, though their
etiology remains debated. Given the vital role of bile fluid in digestive processes within the …

[HTML][HTML] Mechanisms Underlying the Rarity of Skeletal Muscle Cancers

DS Kump - International Journal of Molecular Sciences, 2024 - mdpi.com
Skeletal muscle (SKM), despite comprising~ 40% of body mass, rarely manifests cancer.
This review explores the mechanisms that help to explain this rarity, including unique SKM …