Ferroptosis: a double-edged sword mediating immune tolerance of cancer

Q Dang, Z Sun, Y Wang, L Wang, Z Liu, X Han - Cell death & disease, 2022 - nature.com
The term ferroptosis was put forward in 2012 and has been researched exponentially over
the past few years. Ferroptosis is an unconventional pattern of iron-dependent programmed …

Role of vascular smooth muscle cell phenotypic switching and calcification in aortic aneurysm formation: involvement of vitamin K-dependent processes

P Petsophonsakul, M Furmanik, R Forsythe… - … , and vascular biology, 2019 - Am Heart Assoc
Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood
vessel degenerates, leading to dilation and eventually vessel wall rupture. Recently, it was …

A non-canonical vitamin K cycle is a potent ferroptosis suppressor

E Mishima, J Ito, Z Wu, T Nakamura, A Wahida, S Doll… - Nature, 2022 - nature.com
Ferroptosis, a non-apoptotic form of cell death marked by iron-dependent lipid peroxidation,
has a key role in organ injury, degenerative disease and vulnerability of therapy-resistant …

Role of vitamin K in intestinal health

Y Lai, H Masatoshi, Y Ma, Y Guo, B Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Intestinal diseases, such as inflammatory bowel diseases (IBDs) and colorectal cancer
(CRC) generally characterized by clinical symptoms, including malabsorption, intestinal …

Emerging significance and therapeutic targets of ferroptosis: a potential avenue for human kidney diseases

J Li, S Zheng, Y Fan, K Tan - Cell Death & Disease, 2023 - nature.com
Kidney diseases remain one of the leading causes of human death and have placed a
heavy burden on the medical system. Regulated cell death contributes to the pathology of a …

The role of vitamin K in humans: implication in aging and age-associated diseases

DS Popa, G Bigman, ME Rusu - Antioxidants, 2021 - mdpi.com
As human life expectancy is rising, the incidence of age-associated diseases will also
increase. Scientific evidence has revealed that healthy diets, including good fats, vitamins …

The developing oligodendrocyte: key cellular target in brain injury in the premature infant

JJ Volpe, HC Kinney, FE Jensen… - International Journal of …, 2011 - Elsevier
Brain injury in the premature infant, a problem of enormous importance, is associated with a
high risk of neurodevelopmental disability. The major type of injury involves cerebral white …

Tau contributes to sevoflurane-induced neurocognitive impairment in neonatal mice

Y Yu, Y Yang, H Tan, M Boukhali, A Khatri, Y Yu… - …, 2020 - pubs.asahq.org
Background Sevoflurane anesthesia induces Tau phosphorylation and cognitive impairment
in neonatal but not in adult mice. This study tested the hypothesis that differences in brain …

Vitamin K as a diet supplement with impact in human health: current evidence in age-related diseases

DC Simes, CSB Viegas, N Araújo, C Marreiros - Nutrients, 2020 - mdpi.com
Vitamin K health benefits have been recently widely shown to extend beyond blood
homeostasis and implicated in chronic low-grade inflammatory diseases such as …

[HTML][HTML] ESPEN micronutrient guideline

MM Berger, A Shenkin, A Schweinlin, K Amrein… - Clinical Nutrition, 2022 - Elsevier
Background Trace elements and vitamins, named together micronutrients (MNs), are
essential for human metabolism. Recent research has shown the importance of MNs in …