Exploring the properties and potential of the neural extracellular matrix for next‐generation regenerative therapies

JA Ortega, GP Soares de Aguiar… - Wiley …, 2024 - Wiley Online Library
The extracellular matrix (ECM) is a dynamic and complex network of proteins and molecules
that surrounds cells and tissues in the nervous system and orchestrates a myriad of …

Unlocking the adenosine receptor mechanism of the tumour immune microenvironment

Y Han, C Dong, M Hu, X Wang, G Wang - Frontiers in Immunology, 2024 - frontiersin.org
The suppressive tumour microenvironment significantly hinders the efficacy of
immunotherapy in treating solid tumors. In this context, stromal cells, such as tumour …

Advanced strategies in 3D bioprinting for vascular tissue engineering and disease modelling using smart bioinks

JJ Kim, DW Cho - Virtual and Physical Prototyping, 2024 - Taylor & Francis
ABSTRACT Advanced three-dimensional (3D) bioprinting technology enables the precise
production of complex vascular structures and biomimetic models, driving advancements in …

3D engineering of diseased blood vessels for integrative in vitro–in silico mechanobiology study

W Park, JS Lee, MJ Choi, WW Cho, SH Lee… - …, 2024 - iopscience.iop.org
Vascular diseases are complex conditions orchestrated by multiple factors, including cellular
components, biochemical stimuli, and mechanical forces. Despite the advancement of …

Multi‐Organ Microphysiological Systems Targeting Specific Organs for Recapitulating Disease Phenotypes via Organ Crosstalk

JJ Kim, M Bae, DW Cho - Small Science, 2024 - Wiley Online Library
Various systemic metabolic diseases arise from prolonged crosstalk across multiple organs,
triggering serious impairments in various physiological systems. These diseases are …

Comparative proteomic analysis of the composition of decellularized extracellular matrix (dECM) and dECM-based inks as compared to the native tissue

A Irastorza, P Vazquez-Aristizabal, P Guerrero… - bioRxiv, 2024 - biorxiv.org
Regenerative medicine and tissue engineering approaches based on the use of 3D-
bioprinted decellularized extracellular matrix (dECM) present the advantage of a relatively …