Pulmonary delivery is an alternative route of administration with numerous advantages over
conventional routes of administration. It provides low enzymatic exposure, fewer systemic …

Nanocarriers have been increasingly proposed for lung drug delivery applications. The
strategy of combining the intrinsic and more general advantages of the nanostructures with …

Drug therapies for acute lung injury (ALI) are far from satisfactory, primarily because drugs
cannot specifically target the lungs. Direct delivery of drugs to the deep alveolar regions by …

Based on the drug repositioning strategy, niclosamide (NCL) has shown potential
applications for treating COVID-19. However, the development of new formulations for …

This study aimed to develop a dry powder inhaler (DPI) formulation for enhanced deep lung
delivery of rifampicin using dextrans of different molecular weights. Porous particles were …

Nanoparticle (NP)-based materials have breakthrough applications in many fields of life,
such as in engineering, communications and textiles industries; food and bioenvironmental …

This manuscript critically reviews the design and delivery of spray-dried particles for the
achievement of high total lung doses (TLD) with a portable dry powder inhaler. We introduce …

Globally, the increase of pathogenic bacteria with antibiotic-resistant characteristics has
become a critical challenge in medical treatment. The misuse of conventional antibiotics to …

Dry powder inhalers' performances rely on the optimal combination of the therapeutic
efficacy of the drug (pharmaceutical research) and the effectiveness of the delivery system …

Highlights•Inhalable porous mixed-matrix microspheres were successfully prepared.•The
cumulative release of mixed-matrix microspheres was much higher.•Porous mixed-matrix …