Perspectives on skeletal muscle stem cells
F Relaix, M Bencze, MJ Borok, A Der Vartanian… - Nature …, 2021 - nature.com
Skeletal muscle has remarkable regeneration capabilities, mainly due to its resident muscle
stem cells (MuSCs). In this review, we introduce recently developed technologies and the …
stem cells (MuSCs). In this review, we introduce recently developed technologies and the …
The Duchenne muscular dystrophy gene and cancer
Abstract Background Mutation of the Duchenne muscular dystrophy (DMD) gene causes
Duchenne and Becker muscular dystrophy, degenerative neuromuscular disorders that …
Duchenne and Becker muscular dystrophy, degenerative neuromuscular disorders that …
Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup
Embryonal rhabdomyosarcoma (ERMS) of the uterus has recently been shown to frequently
harbor DICER1 mutations. Interestingly, only rare cases of extrauterine DICER1-associated …
harbor DICER1 mutations. Interestingly, only rare cases of extrauterine DICER1-associated …
Increased susceptibility to cerebral microhemorrhages is associated with imaging signs of microvascular degeneration in the retina in an insulin-like growth factor 1 …
LR Miller, S Tarantini, Á Nyúl-Tóth… - Frontiers in Aging …, 2022 - frontiersin.org
Age-related cerebrovascular defects contribute to vascular cognitive impairment and
dementia (VCID) as well as other forms of dementia. There has been great interest in …
dementia (VCID) as well as other forms of dementia. There has been great interest in …
PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors
Development is regulated by various factors, including protein methylation status. While
PRMT5 is well known for its roles in oncogenesis by mediating symmetric di-methylation of …
PRMT5 is well known for its roles in oncogenesis by mediating symmetric di-methylation of …
[HTML][HTML] Injury primes mutation-bearing astrocytes for dedifferentiation in later life
HS Ragdale, M Clements, W Tang, E Deltcheva… - Current Biology, 2023 - cell.com
Despite their latent neurogenic potential, most normal parenchymal astrocytes fail to
dedifferentiate to neural stem cells in response to injury. In contrast, aberrant lineage …
dedifferentiate to neural stem cells in response to injury. In contrast, aberrant lineage …
Empowering muscle stem cells for the treatment of duchenne muscular dystrophy
RL Filippelli, NC Chang - Cells Tissues Organs, 2022 - karger.com
Duchenne muscular dystrophy (DMD) is a devastating and debilitating muscle degenerative
disease affecting 1 in every 3,500 male births worldwide. DMD is progressive and fatal; …
disease affecting 1 in every 3,500 male births worldwide. DMD is progressive and fatal; …
[HTML][HTML] The CARM1 transcriptome and arginine methylproteome mediate skeletal muscle integrative biology
Objective Coactivator-associated arginine methyltransferase 1 (CARM1) catalyzes the
methylation of arginine residues on target proteins to regulate critical processes in health …
methylation of arginine residues on target proteins to regulate critical processes in health …
Constricted migration modulates stem cell differentiation
Tissue regeneration at an injured site depends on proliferation, migration, and differentiation
of resident stem or progenitor cells, but solid tissues are often sufficiently dense and …
of resident stem or progenitor cells, but solid tissues are often sufficiently dense and …
Preclinical in vivo modeling of pediatric sarcoma—promises and limitations
Pediatric sarcomas are an extremely heterogeneous group of genetically distinct diseases.
Despite the increasing knowledge on their molecular makeup in recent years, true …
Despite the increasing knowledge on their molecular makeup in recent years, true …