The role of dopamine in schizophrenia from a neurobiological and evolutionary perspective: old fashioned, but still in vogue
R Brisch, A Saniotis, R Wolf, H Bielau… - Frontiers in …, 2014 - frontiersin.org
Dopamine is an inhibitory neurotransmitter involved in the pathology of schizophrenia. The
revised dopamine hypothesis states that dopamine abnormalities in the mesolimbic and …
revised dopamine hypothesis states that dopamine abnormalities in the mesolimbic and …
Interactions between variation in candidate genes and environmental factors in the etiology of schizophrenia and bipolar disorder: a systematic review
Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …
The neural circuitry supporting goal maintenance during cognitive control: a comparison of expectancy AX-CPT and dot probe expectancy paradigms
Goal maintenance is an aspect of cognitive control that has been identified as critical for
understanding psychopathology according to criteria of the NIMH-sponsored CNTRICS …
understanding psychopathology according to criteria of the NIMH-sponsored CNTRICS …
A review of molecular genetic studies of neurocognitive deficits in schizophrenia
Schizophrenia is a complex and debilitating illness with strong genetic loading. In line with
its heterogeneous symptomatology, evidence suggests genetic etiologies for the …
its heterogeneous symptomatology, evidence suggests genetic etiologies for the …
Task-related fronto-striatal functional connectivity during working memory performance in schizophrenia
Working memory (WM) deficits and associated brain dysfunction are among the most well
replicated candidate endophenotypic processes in schizophrenia. However, previous …
replicated candidate endophenotypic processes in schizophrenia. However, previous …
Familial aggregation of MATRICS Consensus Cognitive Battery scores in a large sample of outpatients with schizophrenia and their unaffected relatives
BackgroundThe increased use of the MATRICS Consensus Cognitive Battery (MCCB) to
investigate cognitive dysfunctions in schizophrenia fostered interest in its sensitivity in the …
investigate cognitive dysfunctions in schizophrenia fostered interest in its sensitivity in the …
Effects of ketamine on context-processing performance in monkeys: a new animal model of cognitive deficits in schizophrenia
RK Blackman, AW MacDonald… - …, 2013 - nature.com
Cognitive deficits are at the crux of why many schizophrenia patients have poor functional
outcomes. One of the cognitive symptoms experienced by schizophrenia patients is a deficit …
outcomes. One of the cognitive symptoms experienced by schizophrenia patients is a deficit …
A meta-analysis of context integration deficits across the schizotypy spectrum using AX-CPT and DPX tasks.
Schizotypy and schizophrenia involve disrupted context integration (CI), the ability to
assimilate internal and external information into coherent mental representations. Research …
assimilate internal and external information into coherent mental representations. Research …
Mapping dopaminergic deficiencies in the substantia nigra/ventral tegmental area in schizophrenia
MW Rice, RC Roberts, M Melendez-Ferro… - Brain Structure and …, 2016 - Springer
Previous work from our laboratory showed deficits in tyrosine hydroxylase protein
expression within the substantia nigra/ventral tegmental area (SN/VTA) in schizophrenia …
expression within the substantia nigra/ventral tegmental area (SN/VTA) in schizophrenia …
Impaired context processing is attributable to global neuropsychological impairment in schizophrenia and psychotic bipolar disorder
Background: Context processing may reflect a specific cognitive impairment in
schizophrenia. Whether impaired context processing is observed across psychotic disorders …
schizophrenia. Whether impaired context processing is observed across psychotic disorders …