We have systematically reviewed the presence, functional responses and regulation of α1‐,
α2‐and β‐adrenoceptors in the bladder, urethra and prostate, with special emphasis on …

Objective: To determine the validity coefficient of the total prostate gland volume as an
expression of the transition zone (TZ) volume. To test the hypothesis of hyperinsulinaemia …

Routine exposure to artificial light at night (ALAN) in work, home, and community settings is
linked with increased risk of breast and prostate cancer (BC, PC) in normally sighted women …

Recent evidence from our laboratory has demonstrated thatα1-adrenoceptor antagonists
doxazosin and terazosin induced apoptosis in prostate epithelial and smooth muscle cells in …

The main use of α1-adrenoceptor (AR) antagonists in urology has been to treat lower urinary
tract symptoms (LUTS) in men with benign prostatic obstruction (BPO). The beneficial effects …

PURPOSE: Doxazosin and terazosin are known to relax prostate smooth muscle through
blockade of α1-adrenergic innervation to the prostate. This action alone however does not …

Recent evidence suggests that the quinazoline-based α1-adrenoceptor antagonists,
doxazosin and terazosin, exhibit a potent apoptotic effect against prostate tumor epithelial …

Prostatic α1‐adrenoceptors are known to be involved in the pathophysiology of lower
urinary tract symptoms (LUTS) in patients with benign prostate obstruction (BPO). It is widely …

Previous studies documented the ability of quinazoline-based α1-adrenoceptor antagonists
to induce apoptosis in prostate cancer cells via an α1-adrenoceptor-independent …

PURPOSE:: Cyclooxygenase-2 (COX-2) is expressed in human BPH tissue and displays
either a pro-inflammatory effect or a proliferative effect on prostate cells. The aim of this study …