[HTML][HTML] Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs

C Zhou, B Molinie, K Daneshvar, JV Pondick, J Wang… - Cell reports, 2017 - cell.com
Summary N 6-methyladenosine (m 6 A) is the most abundant internal modification of
mRNAs and is implicated in all aspects of post-transcriptional RNA metabolism. However …

Identifying a miRNA signature for predicting the stage of breast cancer

S Yerukala Sathipati, SY Ho - Scientific reports, 2018 - nature.com
Breast cancer is a heterogeneous disease and one of the most common cancers among
women. Recently, microRNAs (miRNAs) have been used as biomarkers due to their …

[HTML][HTML] MicroRNAs as targets for cancer diagnosis: Interests and limitations

B Shademan, V Karamad, A Nourazarian… - Advanced …, 2023 - ncbi.nlm.nih.gov
MicroRNAs are small RNAs with ability to attach to the large number of RNA that regulate
gene expression on post-transcriptional level via inhibition or degradation of specific …

Amplification of 8p11. 23 in cancers and the role of amplicon genes

IA Voutsadakis - Life Sciences, 2021 - Elsevier
Copy number alterations are widespread in cancer genomes and are part of the genomic
instability underlying the pathogenesis of neoplastic diseases. Recurrent copy number …

[HTML][HTML] MiR-199a-5p suppresses non-small cell lung cancer via targeting MAP3K11

Y Li, D Wang, X Li, Y Shao, Y He, H Yu, Z Ma - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) comprise a class of short, non-coding RNAs that directly target 3′
UTR of mRNA, causing subsequent degradation or suppression of translation. Here, we …

Circular RNA circRUNX1 promotes papillary thyroid cancer progression and metastasis by sponging MiR-296-3p and regulating DDHD2 expression

J Chu, L Tao, T Yao, Z Chen, X Lu, L Gao, L Fang… - Cell Death & …, 2021 - nature.com
Papillary thyroid cancer (PTC) has a continuously increasing incidence and imposes a
heavy medical burden to individuals and society due to its high proportion of lymph node …

MiR-503 inhibited cell proliferation of human breast cancer cells by suppressing CCND1 expression

J Long, C Ou, H Xia, Y Zhu, D Liu - Tumor Biology, 2015 - Springer
Breast cancer is one of the most common malignancies and a major cause of cancer-related
mortality all over the world. A growing body of reports revealed that microRNAs play …

An integrative transcriptomics approach identifies miR-503 as a candidate master regulator of the estrogen response in MCF-7 breast cancer cells

J Baran-Gale, JE Purvis, P Sethupathy - Rna, 2016 - rnajournal.cshlp.org
Estrogen receptor α (ERα) is an important biomarker of breast cancer severity and a
common therapeutic target. In response to estrogen, ERα stimulates a dynamic …

miR-503-3p induces apoptosis of lung cancer cells by regulating p21 and CDK4 expression

Y Sun, L Li, S Xing, Y Pan, Y Shi, L Zhang… - Cancer …, 2017 - content.iospress.com
Studies have shown that microRNAs (miRNAs) can promote or suppress tumor growth and
therefore act as targets for cancer therapy. Hsa-miR-503-5p, a mature miRNA derived from …

miR-503 suppresses tumor cell proliferation and metastasis by directly targeting RNF31 in prostate cancer

J Guo, X Liu, M Wang - Biochemical and biophysical research …, 2015 - Elsevier
Microarray data analyses were performed to search for metastasis-associated oncogenes in
prostate cancer (PCa). RNF31 mRNA expressions in tumor tissues and benign prostate …