Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies

J Xie, Y Wang, W Choi, P Jangili, Y Ge, Y Xu… - Chemical Society …, 2021 - pubs.rsc.org
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …

Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application

T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …

The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X Xie… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

Self-assembling nucleic acid nanostructures functionalized with aptamers

A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Challenges and perspectives of DNA nanostructures in biomedicine

A Keller, V Linko - Angewandte Chemie International Edition, 2020 - Wiley Online Library
DNA nanotechnology holds substantial promise for future biomedical engineering and the
development of novel therapies and diagnostic assays. The subnanometer‐level …

Manipulating tumor hypoxia toward enhanced photodynamic therapy (PDT)

J Dang, H He, D Chen, L Yin - Biomaterials Science, 2017 - pubs.rsc.org
Photodynamic therapy (PDT) is considered a promising approach for the treatment of cancer
and is achieved via the photosensitizer (PS)-mediated incomplete reduction of oxygen upon …

Chemistry can make strict and fuzzy controls for bio-systems: DNA nanoarchitectonics and cell-macromolecular nanoarchitectonics

M Komiyama, K Yoshimoto, M Sisido… - Bulletin of the Chemical …, 2017 - academic.oup.com
In this review, we introduce two kinds of bio-related nanoarchitectonics, DNA
nanoarchitectonics and cell-macromolecular nanoarchitectonics, both of which are basically …

Tetrahedral DNA nanostructures for effective treatment of cancer: advances and prospects

J Yan, X Zhan, Z Zhang, K Chen, M Wang… - Journal of …, 2021 - Springer
Recently, DNA nanostructures with vast application potential in the field of biomedicine,
especially in drug delivery. Among these, tetrahedral DNA nanostructures (TDN) have …

Three-dimensional DNA nanostructures to improve the hyperbranched hybridization chain reaction

J Wang, DX Wang, JY Ma, YX Wang, DM Kong - Chemical Science, 2019 - pubs.rsc.org
Nonenzymatic nucleic acid amplification techniques (eg the hybridization chain reaction,
HCR) have shown promising potential for amplified detection of biomarkers. However, the …

[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules

W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …