Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix: a meta-analysis of individual patient data

R Romero, A Conde-Agudelo, E Da Fonseca… - American journal of …, 2018 - Elsevier
Background The efficacy of vaginal progesterone for preventing preterm birth and adverse
perinatal outcomes in singleton gestations with a short cervix has been questioned after …

The prediction of preterm delivery: What is new?

N Suff, L Story, A Shennan - Seminars in Fetal and Neonatal Medicine, 2019 - Elsevier
Preterm birth, defined as birth occurring prior to 37 weeks gestation, is a serious obstetric
problem accounting for 11% of pregnancies worldwide. It is associated with significant …

Cervicovaginal microbiota and local immune response modulate the risk of spontaneous preterm delivery

MA Elovitz, P Gajer, V Riis, AG Brown… - Nature …, 2019 - nature.com
Failure to predict and understand the causes of preterm birth, the leading cause of neonatal
morbidity and mortality, have limited effective interventions and therapeutics. From a cohort …

Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short …

A Conde-Agudelo, R Romero, E Da Fonseca… - American journal of …, 2018 - Elsevier
Background An indirect comparison meta-analysis published in 2013 reported that both
vaginal progesterone and cerclage are equally efficacious for preventing preterm birth and …

Prediction of preterm birth: maternal characteristics, ultrasound markers, and biomarkers: an updated overview

ZA Oskovi Kaplan, AS Ozgu-Erdinc - Journal of pregnancy, 2018 - Wiley Online Library
There is not a single or combined screening method for preterm birth with high sensitivity
which will truly identify the women at risk for preterm birth while also with high specificity to …

Screening for spontaneous preterm birth and resultant therapies to reduce neonatal morbidity and mortality: A review

AV Glover, TA Manuck - Seminars in Fetal and Neonatal Medicine, 2018 - Elsevier
Despite considerable effort aimed at decreasing the incidence of spontaneous preterm birth,
it remains the leading cause of perinatal morbidity and mortality. Screening strategies are …

Cervical pessary for prevention of preterm birth in individuals with a short cervix: the TOPS randomized clinical trial

MK Hoffman, RG Clifton, JR Biggio, GR Saade… - JAMA, 2023 - jamanetwork.com
Importance A short cervix as assessed by transvaginal ultrasound is an established risk
factor for preterm birth. Study findings for a cervical pessary to prevent preterm delivery in …

Next generation strategies for preventing preterm birth

HC Zierden, RL Shapiro, K DeLong, DM Carter… - Advanced drug delivery …, 2021 - Elsevier
Preterm birth (PTB) is defined as delivery before 37 weeks of gestation. Globally, 15 million
infants are born prematurely, putting these children at an increased risk of mortality and …

Mouse models of preterm birth: suggested assessment and reporting guidelines

R McCarthy, C Martin-Fairey, DK Sojka… - Biology of …, 2018 - academic.oup.com
Preterm birth affects approximately 1 out of every 10 births in the United States, leading to
high rates of mortality and long-term negative health consequences. To investigate the …

Electrohysterography in the diagnosis of preterm birth: a review

J Garcia-Casado, Y Ye-Lin… - Physiological …, 2018 - iopscience.iop.org
Preterm birth (PTB) is one of the most common and serious complications in pregnancy.
About 15 million preterm neonates are born every year, with ratios of 10–15% of total births …