Abstract The Human BioMolecular Atlas Program (HuBMAP) aims to create a multi-scale
spatial atlas of the healthy human body at single-cell resolution by applying advanced …

The ability to localize hundreds of macromolecules to discrete locations, structures and cell
types in a tissue is a powerful approach to understand the cellular and spatial organization …

A large-scale multimodal atlas that includes major kidney regions is lacking. Here, we
employed simultaneous high-throughput single-cell ATAC/RNA sequencing (SHARE-seq) …

Spatial transcriptomics (ST) enables interrogating the molecular composition of tissue with
ever-increasing resolution, depth, and sensitivity. However, costs, rapidly evolving …

Kidney stone, one of the oldest known diseases, has plagued humans for centuries,
consistently imposing a heavy burden on patients and healthcare systems worldwide due to …

Chronic kidney disease (CKD) and acute kidney injury (AKI) are heterogeneous syndromes
defined clinically by serial measures of kidney function. Each condition possesses strong …

Background: The first spatially resolved transcriptomics platforms, GeoMx (Nanostring) and
Visium (10x Genomics) were launched in 2019 and were recognized as the method of the …

Recent advancements in modern science have provided robust tools for drug discovery. The
rapid development of transcriptome sequencing technologies has given rise to single-cell …

The recent arrival of high-resolution spatial transcriptomics (ST) technologies is generating a
veritable revolution in life sciences, enabling biomolecules to be measured in their native …

Vascular calcification (VC) is considered a common pathological process in various vascular
diseases. Accumulating studies have confirmed that VC is involved in the inflammatory …