Ageing is a composite process that involves numerous changes at the cellular, tissue, organ
and whole-body levels. These changes result in decreased functioning of the organism and …

Highlights•Aging is the major risk factor for AMD.•The macula contains more than 60 kinds of
cells that may age at different rates.•The retinal aging in AMD is determined by its interplay …

The discrepancy between chronological age and the apparent age of the brain based on
neuroimaging data—the brain age delta—has emerged as a reliable marker of brain health …

Defects in brain energy metabolism and proteopathic stress are implicated in age-related
degenerative neuronopathies, exemplified by Alzheimer's disease (AD) and Parkinson's …

The imaging-based method of brainAGE aims to characterize an individual's vulnerability to
age-related brain changes. The present study systematically reviewed brainAGE findings in …

The association between age and language recovery in stroke remains unclear. Here, we
used neuroimaging data to estimate brain age, a measure of structural integrity, and …

Previous studies have observed a significant comorbidity between Alzheimer's disease (AD)
and some other neuropsychiatric disorders. However, the mechanistic connections between …

Unveiling the details of white matter (WM) maturation throughout ageing is a fundamental
question for understanding the ageing brain. In an extensive comparison of brain age …

Increased life expectancy has led to a rise in age-related disorders including neurological
diseases such as Alzheimer's disease and Parkinson's disease. Limited progress has been …

Brain age is a neuroimaging-based biomarker of aging. This study examined whether the
difference between brain age and chronological age (brain-PAD) is associated with …