Mass spectrometry‐based high‐throughput proteomics and its role in biomedical studies and systems biology

CB Messner, V Demichev, Z Wang, J Hartl… - …, 2023 - Wiley Online Library
There are multiple reasons why the next generation of biological and medical studies
require increasing numbers of samples. Biological systems are dynamic, and the effect of a …

[HTML][HTML] Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

SE O'Bryant, V Gupta, K Henriksen, M Edwards… - Alzheimer's & …, 2015 - Elsevier
The lack of readily available biomarkers is a significant hindrance toward progressing to
effective therapeutic and preventative strategies for Alzheimer's disease (AD). Blood-based …

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

Y Perez-Riverol, J Bai, C Bandla… - Nucleic acids …, 2022 - academic.oup.com
Abstract The PRoteomics IDEntifications (PRIDE) database (https://www. ebi. ac. uk/pride/) is
the world's largest data repository of mass spectrometry-based proteomics data. PRIDE is …

Standard operating procedures for serum and plasma collection: early detection research network consensus statement standard operating procedure integration …

MK Tuck, DW Chan, D Chia, AK Godwin… - Journal of proteome …, 2009 - ACS Publications
Specimen collection is an integral component of clinical research. Specimens from subjects
with various stages of cancers or other conditions, as well as those without disease, are …

[HTML][HTML] Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease

DM Good, P Zürbig, A Argiles, HW Bauer… - Molecular & cellular …, 2010 - ASBMB
Because of its availability, ease of collection, and correlation with physiology and pathology,
urine is an attractive source for clinical proteomics/peptidomics. However, the lack of …

[HTML][HTML] Urine in clinical proteomics

S Decramer, AG de Peredo, B Breuil, H Mischak… - Molecular & cellular …, 2008 - ASBMB
Urine has become one of the most attractive biofluids in clinical proteomics as it can be
obtained non-invasively in large quantities and is stable compared with other biofluids. The …

[HTML][HTML] Isotope-labeled protein standards: toward absolute quantitative proteomics

V Brun, A Dupuis, A Adrait, M Marcellin… - Molecular & Cellular …, 2007 - ASBMB
Diagnostic development and public health surveillance require technologies that provide
specific identification and absolute quantification of protein biomarkers. Beside …

Recommendations for biomarker identification and qualification in clinical proteomics

H Mischak, G Allmaier, R Apweiler, T Attwood… - Science translational …, 2010 - science.org
Clinical proteomics has yielded some early positive results—the identification of potential
disease biomarkers—indicating the promise for this analytical approach to improve the …

[HTML][HTML] Improvement in long-term renal graft survival due to CMV prophylaxis with oral ganciclovir: results of a randomized clinical trial

V Kliem, L Fricke, T Wollbrink, M Burg… - American Journal of …, 2008 - Elsevier
Oral ganciclovir prophylaxis and intravenous preemptive therapy are competitive
approaches to prevent cytomegalovirus (CMV) disease after renal transplantation. This trial …

[HTML][HTML] Personalized proteomics: the future of precision medicine

TT Duarte, CT Spencer - Proteomes, 2016 - mdpi.com
Medical diagnostics and treatment has advanced from a one size fits all science to treatment
of the patient as a unique individual. Currently, this is limited solely to genetic analysis …