Prevalence and incidence of Huntington's disease: an updated systematic review and meta‐analysis

A Medina, Y Mahjoub, L Shaver… - Movement …, 2022 - Wiley Online Library
The incidence and prevalence of Huntington's disease (HD) based on a systematic review
and meta‐analysis of 20 studies published from 1985 to 2010 was estimated at 0.38 per …

The global prevalence of Huntington's disease: a systematic review and discussion

SS Baig, M Strong, OWJ Quarrell - Neurodegenerative disease …, 2016 - Taylor & Francis
The ascertained prevalence of Huntington's disease (HD) increased significantly following
the provision of diagnostic testing. A systematic review was conducted to estimate the …

New biological insights on X and Y chromosome-bearing spermatozoa

MS Rahman, MG Pang - Frontiers in cell and developmental biology, 2020 - frontiersin.org
A spermatozoon is a male germ cell capable of fertilizing an oocyte and carries genetic
information for determining the sex of the offspring. It comprises autosomes and an X (X …

Genetics of Huntington disease

MA Nance - Handbook of clinical neurology, 2017 - Elsevier
In this chapter, we review the evolution of our understanding of the genetic aspects of HD,
and the applications of our understanding in the management of Huntington's disease …

22 Years of predictive testing for Huntington's disease: the experience of the UK Huntington's Prediction Consortium

SS Baig, M Strong, E Rosser, NV Taverner… - European Journal of …, 2016 - nature.com
Huntington's disease (HD) is a progressive neurodegenerative condition. At-risk individuals
have accessed predictive testing via direct mutation testing since 1993. The UK Huntington's …

Epidemiology of Huntington disease

C Kay, MR Hayden, BR Leavitt - Handbook of clinical neurology, 2017 - Elsevier
Huntington disease (HD) is an autosomal-dominant neurologic disorder caused by an
expanded CAG trinucleotide repeat mutation in patients with characteristic motor signs and …

Modeling manifest Huntington's disease prevalence using diagnosed incidence and survival time

V Crowell, R Houghton, A Tomar, T Fernandes… - …, 2021 - karger.com
Introduction: Understanding the epidemiology of Huntington's disease (HD) is key to
assessing disease burden and the healthcare resources required to meet patients' needs …

Incidence of adult Huntington's disease in the UK: a UK-based primary care study and a systematic review

NS Wexler, L Collett, AR Wexler, MD Rawlins… - BMJ open, 2016 - bmjopen.bmj.com
Objectives The prevalence of Huntington's disease (HD) recorded in the UK primary care
records has increased twofold between 1990 and 2010. This investigation was undertaken …

Epidemiology of Huntington's disease in Finland

JOT Sipilä, M Hietala, A Siitonen, M Päivärinta… - Parkinsonism & related …, 2015 - Elsevier
Object To estimate the prevalence of Huntington's disease (HD) in Finland. Methods
Persons diagnosed with HD from 1987 to 2010 were identified in the national registers and …

The neuroprotective role of BCG vaccine in movement disorders: A review

NG Yedke, P Kumar - … (Formerly Current Drug Targets-CNS & …, 2024 - benthamdirect.com
Bacillus Calmette-Guérin (BCG) is the first developed vaccine to prevent tuberculosis (TB)
and is the world's most widely used vaccine. It has a reconcilable defense in opposition to …