Reactive oxygen species oxidize STING and suppress interferon production
Reactive oxygen species (ROS) are by-products of cellular respiration that can promote
oxidative stress and damage cellular proteins and lipids. One canonical role of ROS is to …
oxidative stress and damage cellular proteins and lipids. One canonical role of ROS is to …
A cryptic homotypic interaction motif of insect STING is required for its antiviral signaling
X Wang, D Wei, Y Pan, J Liu, X Xiao, Q Xia… - Developmental & …, 2024 - Elsevier
Stimulator of interferon genes (STING) mediates innate immune response upon binding to
cyclic GMP-AMP (cGAMP). It recruits tank-binding kinase 1 (TBK1) and transcription factor …
cyclic GMP-AMP (cGAMP). It recruits tank-binding kinase 1 (TBK1) and transcription factor …