Spinal metastases 2021: a review of the current state of the art and future directions

DM Sciubba, Z Pennington, MW Colman, CR Goodwin… - The Spine Journal, 2021 - Elsevier
Spinal metastases are an increasing societal health burden secondary to improvements in
systemic therapy. Estimates indicate that 100,000 or more people have symptomatic spine …

Systemic considerations for the surgical treatment of spinal metastatic disease: a scoping literature review

MA MacLean, CJ Touchette, M Georgiopoulos… - The Lancet …, 2022 - thelancet.com
Systemic assessment is a pillar in the neurological, oncological, mechanical, and systemic
(NOMS) decision-making framework for the treatment of patients with spinal metastatic …

International external validation of the SORG machine learning algorithms for predicting 90-day and one-year survival of patients with spine metastases using a …

JJ Yang, CW Chen, MS Fourman, MER Bongers… - The Spine Journal, 2021 - Elsevier
Abstract Background Context Accurately predicting the survival of patients with spinal
metastases is important for guiding surgical intervention. The SORG machine-learning (ML) …

Does the SORG algorithm generalize to a contemporary cohort of patients with spinal metastases on external validation?

MER Bongers, AV Karhade, J Villavieja, OQ Groot… - The Spine Journal, 2020 - Elsevier
Abstract BACKGROUND CONTEXT The SORG machine-learning algorithms were
previously developed for preoperative prediction of overall survival in spinal metastatic …

[HTML][HTML] Diagnostic and therapeutic approach of artificial intelligence in neuro-oncological diseases

D Venkatesan, A Elangovan, H Winster… - … and Bioelectronics: X, 2022 - Elsevier
Neuro-oncological diseases are rare and their fatality rate is increased in patients due to
advance disease development despite of the recent outcomes on neuro-oncological …

Development and external validation of predictive algorithms for six-week mortality in spinal metastasis using 4,304 patients from five institutions

AV Karhade, B Fenn, OQ Groot, AA Shah, HK Yen… - The Spine Journal, 2022 - Elsevier
BACKGROUND CONTEXT Historically, spine surgeons used expected postoperative
survival of 3-months to help select candidates for operative intervention in spinal metastasis …

Prognostic factors associated with surviving less than 3 months vs greater than 3 years specific to spine stereotactic body radiotherapy and late adverse events

KL Zeng, A Sahgal, CL Tseng, S Myrehaug… - …, 2021 - journals.lww.com
BACKGROUND Patient selection is critical for spine stereotactic body radiotherapy (SBRT)
given potential for serious adverse effects and the associated costs. OBJECTIVE To identify …

Impact of spinal instrumentation on neurological outcome in patients with intermediate Spinal Instability Neoplastic Score (SINS)

M Lenschow, M Lenz, N von Spreckelsen, J Ossmann… - Cancers, 2022 - mdpi.com
Simple Summary Spinal epidural metastases are a common complication of malignancies
that can compromise spinal stability and subsequently lead to neurologic deficits in addition …

[HTML][HTML] To operate, or not to operate? Narrative review of the role of survival predictors in patient selection for operative management of patients with metastatic spine …

Z Pennington, J Ehresman, E Cottrill… - … of Neurosurgery: Spine, 2020 - thejns.org
Accurate prediction of patient survival is an essential component of the preoperative
evaluation of patients with spinal metastases. Over the past quarter of a century, a number of …

Prospective study for establishing minimal clinically important differences in patients with surgery for lower extremity metastases

MER Bongers, OQ Groot, QCBS Thio… - Acta …, 2021 - Taylor & Francis
Background The clinical relevance of patient-reported outcomes score changes is often
unclear. Especially in patients undergoing surgery due to lower extremity metastases–where …