Next-generation DNA sequencing methods

ER Mardis - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Recent scientific discoveries that resulted from the application of next-generation DNA
sequencing technologies highlight the striking impact of these massively parallel platforms …

Next-generation sequencing transforms today's biology

SC Schuster - Nature methods, 2008 - nature.com
A new generation of non-Sanger-based sequencing technologies has delivered on its
promise of sequencing DNA at unprecedented speed, thereby enabling impressive scientific …

Grey wolf genomic history reveals a dual ancestry of dogs

A Bergström, DWG Stanton, UH Taron, L Frantz… - Nature, 2022 - nature.com
The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and
they remained widespread throughout the last Ice Age when many other large mammal …

Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal

P Skoglund, BH Northoff, MV Shunkov… - Proceedings of the …, 2014 - National Acad Sciences
One of the main impediments for obtaining DNA sequences from ancient human skeletons is
the presence of contaminating modern human DNA molecules in many fossil samples and …

Comparing ancient DNA preservation in petrous bone and tooth cementum

HB Hansen, PB Damgaard, A Margaryan, J Stenderup… - PloS one, 2017 - journals.plos.org
Large-scale genomic analyses of ancient human populations have become feasible partly
due to refined sampling methods. The inner part of petrous bones and the cementum layer …

[HTML][HTML] Complete genomes reveal signatures of demographic and genetic declines in the woolly mammoth

E Palkopoulou, S Mallick, P Skoglund, J Enk… - Current Biology, 2015 - cell.com
The processes leading up to species extinctions are typically characterized by prolonged
declines in population size and geographic distribution, followed by a phase in which …

Pulling out the 1%: whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries

ML Carpenter, JD Buenrostro, C Valdiosera… - The American Journal of …, 2013 - cell.com
Most ancient specimens contain very low levels of endogenous DNA, precluding the
shotgun sequencing of many interesting samples because of cost. Ancient DNA (aDNA) …

Ancient and modern genomes unravel the evolutionary history of the rhinoceros family

S Liu, MV Westbury, N Dussex, KJ Mitchell… - Cell, 2021 - cell.com
Only five species of the once-diverse Rhinocerotidae remain, making the reconstruction of
their evolutionary history a challenge to biologists since Darwin. We sequenced genomes …

The future of ancient DNA: technical advances and conceptual shifts

M Hofreiter, JLA Paijmans, H Goodchild… - …, 2015 - Wiley Online Library
Technological innovations such as next generation sequencing and DNA hybridisation
enrichment have resulted in multi‐fold increases in both the quantity of ancient DNA …

The genetic prehistory of the New World Arctic

M Raghavan, M DeGiorgio, A Albrechtsen, I Moltke… - Science, 2014 - science.org
I ntroduction Humans first peopled the North American Arctic (northern Alaska, Canada, and
Greenland) around 6000 years ago, leaving behind a complex archaeological record that …